Protein-protein complexes : analysis, modeling and drug design

Protein-protein complexes : analysis, modeling and drug design / edited by Martin Zacharias.

Given the immense progress achieved in elucidating protein-protein complex structures and in the field of protein interaction modeling, there is great demand for a book that gives interested researchers/students a comprehensive overview of the field. This book does just that. It focuses on what can...

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Bibliographic Details
Other Authors: Zacharias, Martin
Format: eBook
Language:English
Published: London : Singapore ; Hackensack, NJ : Imperial College Press ; Distributed by World Scientific Pub. Co., ©2010.
Subjects:
Protein-protein interactions.
Carrier proteins.
Proteins > Conformation.
SCIENCE > Life Sciences > Biochemistry.
Proteins > Conformation
Carrier proteins
Protein-protein interactions
Online Access:Click for online access
Table of Contents:
  • X-ray study of protein-protein complexes and analysis of interfaces / Joel Janin
  • A structural perspective on protein-protein interactions in macromolecular assemblies / Ranjit P. Bahadur
  • Energetics of protein-protein interactions / Ilian Jelesarov
  • Kinetics of biomacromolecular complex formation: theory and experiment / Georgi V. Pachov, Razif R. Gabdoulline and Rebecca C. Wade
  • Evolutionary trace of protein functional determinants / Olivier Lichtarge
  • Protein-protein docking / Adrien Saladin and Chantal Prevost
  • Data-driven docking: using external information to spark the biomolecular rendez-vous / Adrien S.J. Melquiond and Alexandre M.J.J. Bonvin
  • High-resolution protein-protein docking / Nir London and Ora Schueler-Furman
  • Scoring and refinement of predicted protein-protein complexes / Martin Zacharias
  • Motif-mediated protein interactions and their role in disease / Holger Dinkel and Heinrich Sticht
  • Prediction and calculation of protein-protein binding affinities and mutation effects / Sébastien Fiorucci, Serge Antonczak and Jérôme Golebiowski
  • Small-molecule inhibitors of protein-protein interactions / Thorsten Berg
  • Protein dynamics and drug design: the role of molecular simulations / Giulia Morra, Alessandro Genoni and Giorgio Colombo.

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