The quest for the cure : the science and stories behind the next generation of medicines / Brent R. Stockwell.

After more than fifty years of blockbuster drug development, skeptics are beginning to fear we may be reaching the end of drug discovery to combat major diseases. In this engaging book, Brent Stockwell, a leading researcher in the exciting new science of chemical biology, describes this dilemma and...

Full description

Saved in:
Bibliographic Details
Main Author: Stockwell, Brent R. (Author)
Format: eBook
Language:English
Published: New York : Columbia University Press, ©2011.
Subjects:
Online Access:Click for online access

MARC

LEADER 00000cam a2200000 i 4500
001 ocn714301737
003 OCoLC
005 20241006213017.0
006 m o d
007 cr mnu---|||||
008 101220s2011 nyua ob 001 0 eng
010 |a  2010053573 
040 |a DNLM/DLC  |b eng  |e rda  |e pn  |c PUL  |d YDXCP  |d CDX  |d UBY  |d OCLCQ  |d N$T  |d OCLCQ  |d JSTOR  |d OCLCQ  |d OCLCF  |d TEFOD  |d IDEBK  |d EBLCP  |d UKMGB  |d JSTOR  |d TEFOD  |d OCLCQ  |d RECBK  |d DEBBG  |d TOA  |d ZCU  |d OCLCQ  |d MERUC  |d IOG  |d DEGRU  |d OCLCO  |d OCLCA  |d EZ9  |d OCLCO  |d OCLCQ  |d OCLCO  |d OCLCQ  |d UAB  |d OCLCO  |d OCLCQ  |d INARC  |d VNS  |d VTS  |d ICG  |d JBG  |d VT2  |d MLSOD  |d OCLCQ  |d WYU  |d OCLCA  |d LVT  |d STF  |d LEAUB  |d OCLCO  |d DKC  |d OCLCO  |d OCLCQ  |d OCLCO  |d M8D  |d OCLCQ  |d UKAHL  |d OCLCQ  |d K6U  |d OCLCA  |d OCLCO  |d OCLCQ  |d SFB  |d OCLCQ  |d DGITA  |d OCLCO  |d OCLCL  |d HOPLA 
016 7 |a 101549996  |2 DNLM 
019 |a 743405299  |a 759836561  |a 816835408  |a 818855877  |a 979909905  |a 992847973  |a 1036811266  |a 1055393446  |a 1066479783  |a 1087023439  |a 1181903691 
020 |a 9780231525527  |q (electronic bk.) 
020 |a 0231525524  |q (electronic bk.) 
020 |z 9780231152129 
020 |z 0231152124 
020 |z 1283072777 
020 |z 9781283072779 
024 7 |a 10.7312/stoc15212  |2 doi 
035 |a (OCoLC)714301737  |z (OCoLC)743405299  |z (OCoLC)759836561  |z (OCoLC)816835408  |z (OCoLC)818855877  |z (OCoLC)979909905  |z (OCoLC)992847973  |z (OCoLC)1036811266  |z (OCoLC)1055393446  |z (OCoLC)1066479783  |z (OCoLC)1087023439  |z (OCoLC)1181903691 
037 |a 22573/ctt2fsb9w  |b JSTOR 
037 |a 6A403DBD-A09A-48DA-84C4-125EAEB1399F  |b OverDrive, Inc.  |n http://www.overdrive.com 
042 |a pcc 
050 4 |a RM301.25  |b .S76 2011 
072 7 |a MED  |x 023000  |2 bisacsh 
072 7 |a MED  |x 058170  |2 bisacsh 
072 7 |a MED  |x 071000  |2 bisacsh 
072 7 |a MED  |x 072000  |2 bisacsh 
072 7 |a MED071000  |2 bisacsh 
072 7 |a SCI007000  |2 bisacsh 
072 7 |a SOC057000  |2 bisacsh 
072 7 |a TEC009010  |2 bisacsh 
072 7 |a POL028000  |2 bisacsh 
049 |a HCDD 
100 1 |a Stockwell, Brent R.,  |e author. 
245 1 4 |a The quest for the cure :  |b the science and stories behind the next generation of medicines /  |c Brent R. Stockwell. 
260 |a New York :  |b Columbia University Press,  |c ©2011. 
300 |a 1 online resource (xviii, 265 pages) :  |b illustrations (some color) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
504 |a Includes bibliographical references and index. 
505 0 |a The drug discovery crisis -- A new science of molecules -- The birth of the first cancer drugs -- A new company creating drug combinations -- The undruggable RAS protein -- The druggable genome -- Peering inside proteins -- The nature of interactions between proteins -- From protein-protein interactions to personalized medicines -- A revolution in peptide synthesis -- A vast array of drug candidates -- Moving outside the small molecule box -- Accelerating the arrival of next-generation drugs. 
520 |a After more than fifty years of blockbuster drug development, skeptics are beginning to fear we may be reaching the end of drug discovery to combat major diseases. In this engaging book, Brent Stockwell, a leading researcher in the exciting new science of chemical biology, describes this dilemma and the powerful techniques that may bring drug research into the twenty-first century. Filled with absorbing stories of breakthroughs, the book begins with the scientific achievements of the twentieth century that led to today's drug innovations. We learn how the invention of mustard gas in. 
650 0 |a Drug development. 
650 0 |a Drugs  |x Design. 
650 0 |a Proteins  |x Metabolism. 
650 7 |a MEDICAL  |x Drug Guides.  |2 bisacsh 
650 7 |a MEDICAL  |x Nursing  |x Pharmacology.  |2 bisacsh 
650 7 |a MEDICAL  |x Pharmacology.  |2 bisacsh 
650 7 |a MEDICAL  |x Pharmacy.  |2 bisacsh 
650 7 |a Drug development  |2 fast 
650 7 |a Drugs  |x Design  |2 fast 
650 7 |a Proteins  |x Metabolism  |2 fast 
758 |i has work:  |a The quest for the cure (Text)  |1 https://id.oclc.org/worldcat/entity/E39PCGDGRGKpw7bVbxKfPcrtTd  |4 https://id.oclc.org/worldcat/ontology/hasWork 
776 0 8 |i Print version:  |a Stockwell, Brent R.  |t Quest for the cure.  |d New York : Columbia University Press, ©2011  |w (DLC) 2010053573 
856 4 0 |u https://ebookcentral.proquest.com/lib/holycrosscollege-ebooks/detail.action?docID=908342  |y Click for online access 
903 |a EBC-AC 
994 |a 92  |b HCD