Enzyme technologies : metagenomics, evolution, biocatalysis, and biosynthesis / edited by Wu-Kuang Yeh, Hsiu-Chiung Yang, James R. McCarthy.

Enzyme Technologies in Drug Discovery highlights how, what, and where enzymes have become critical in pharmaceutical and biotechnology research. This book provides in-depth reviews of recent developments in biosynthesis, biocatalysis, and the chemical biology of enzymes. This text discusses enzymati...

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Bibliographic Details
Other Authors: Yeh, Wu-Kuang, 1942- (Editor), Yang, Hsiu-Chiung (Editor), McCarthy, James R., 1943- (Editor)
Format: eBook
Language:English
Published: Hoboken, N.J. : Wiley, ©2010.
Series:Chemical biology of enzymes for biotechnology and pharmaceutical applications ; v. 1.
Subjects:
Online Access:Click for online access
Table of Contents:
  • Part A. New approaches to finding and modifying enzymes ; Functional metagenomics as a technique for the discovery of novel enzymes and natural products / Luke A Moe, Matthew D McMahon, Michael G Thomas
  • Directed enzyme and pathway evolution / Jacob Vick, Claudia Schmidt-Dannert
  • Combining natural biodiversity and molecular-directed evolution to develop new industrial biocatalysts and drugs / Laurent Fourage, Céline Ayrinhac, Johann Brot, Christophe Ullmann, Denis Wahler, Jean-Marie Sonet
  • Principles of enzyme optimization for the rapid creation of industrial biocatalysts / Richard J Fox, Lori Giver
  • Part B. Biocatalytic applications ; Enzyme catalysis in the synthesis of active pharmaceutical ingredients / Animesh Goswami
  • Enzymatic processes for the production of pharmaceutical intermediates / David Rozzell, Jim Lalonde
  • Novel developments employing redox enzymes : old enzymes in new clothes / Kurt Faber, Silvia M Glueck, Birgit Seisser, Wolfgang Kroutil
  • Part C. Biosynthetic applications ; Drug discovery and development by combinatorial biosynthesis / Matthew A DeSieno, Carl A Denard, Huimin Zhao
  • Reprogramming daptomycin and A54145 biosynthesis to produce novel lipopeptide antibiotics / Richard H Baltz, Kien T Nguyen, Dylan C Alexander
  • Pathway and enzyme engineering and applications for glycodiversification / Lishan Zhao, Hung-Wen Liu.