Chimpanzees in biomedical and behavioral research : assessing the necessity / Committee on the Use of Chimpanzees in Biomedical and Behavioral Research, Board on Health Sciences Policy, Institute of Medicine, Board on Life Sciences, Division on Earth and Life Studies ; Bruce M. Altevogt [and others], editors ; Institute of Medicine and National Research Council of the National Academies.

"For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as rese...

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Bibliographic Details
Corporate Author:	Committee on the Use of Chimpanzees in Biomedical and Behavioral Research (U.S.)
Other Authors:	Altevogt, Bruce M.
Format:	eBook
Language:	English
Published:	Washington, D.C. : National Academies Press, 2011.
Subjects:	Chimpanzees as laboratory animals. Chimpanzees as laboratory animals > Moral and ethical aspects. Chimpanzees. Laboratory animals. Pan troglodytes (species) MEDICAL > Research. Laboratory animals Chimpanzees Chimpanzees as laboratory animals
Online Access:	Click for online access

Table of Contents:

SUMMARY
STUDY BACKGROUND AND CONTEXT
Origin of Study and Committee Statement of Task
Ethical Considerations
METHODS AND ORGANIZATION OF THE REPORT
INTERNATIONAL POLICIES GUIDING CHIMPANZEE USE
SUMMARY OF CHIMPANZEE RESEARCH
Analysis of Federally Supported Research
Analysis of Private-Sector Supported Research
Criteria That Guide the Current Use of Chimpanzees
PRINCIPLES GUIDING THE USE OF CHIMPANZEES IN RESEARCH
Ethologically Appropriate Physical and Social Environments
Criteria to Assess the Necessity of the Chimpanzee for Biomedical
Research
Criteria for Use of the Chimpanzee in Comparative Genomics and
Behavioral Research
REVIEWING THE NECESSITY OF CURRENT CHIMPANZEE
RESEARCH
Monoclonal Antibodies
Development of Chimpanzee Monoclonal Antibodies
Safety Testing of Monoclonal Antibody Therapies
Respiratory Syncytial Virus
HCV Antiviral Drugs
Therapeutic HCV Vaccine
Prophylactic HCV Vaccine
Comparative Genomics
Altruism
Cognition
FUTURE USE OF CHIMPANZEES IN BIOMEDICAL AND
BEHAVIORAL RESEARCH 64
CONCLUSIONS AND RECOMMENDATIONS 66
APPENDIXES
A References
B Commissioned Paper: Comparison of Immunity to Pathogens in Humans, Chimpanzees, and Macaques
C Information-Gathering Agendas
D Committee Biographies.

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