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ocn805560505 |
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OCoLC |
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20240504213016.0 |
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m o d |
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cr cnu---unuuu |
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120809s2012 nju ob 001 0 eng d |
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|a N$T
|b eng
|e pn
|c N$T
|d MHW
|d E7B
|d YDXCP
|d OCLCQ
|d EBLCP
|d CCO
|d OCLCF
|d OCLCQ
|d COO
|d OCLCQ
|d COCUF
|d VLB
|d ZCU
|d MERUC
|d OCLCQ
|d NJR
|d U3W
|d OCLCQ
|d ICG
|d INT
|d OCLCQ
|d DKC
|d OCLCQ
|d UKAHL
|d OCLCQ
|d HS0
|d OCLCO
|d OCLCQ
|d OCLCA
|d OCLCQ
|d OCLCA
|d OCLCO
|d OCLCQ
|d OCL
|d OCLCO
|d OCLCA
|d OCLCL
|d OCLCQ
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| 020 |
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|a 9781118354315
|q (electronic bk.)
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|a 1118354311
|q (electronic bk.)
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|z 9781118028681
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|z 1118028686
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|z 9781118188330
|q (cloth)
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|a (OCoLC)805560505
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| 050 |
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4 |
|a RM301.4
|b .S84 2012eb
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| 072 |
|
7 |
|a MED
|x 071000
|2 bisacsh
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| 049 |
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|a HCDD
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| 100 |
1 |
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|a Sugano, Kiyohiko.
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| 245 |
1 |
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|a Biopharmaceutics modeling and simulations :
|b theory, practice, methods, and applications /
|c Kiyohiko Sugano.
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| 260 |
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|a Hoboken, N.J. :
|b Wiley-Blackwell ;
|a Chichester :
|b John Wiley [distributor],
|c 2012.
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| 300 |
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|a 1 online resource (1 volume)
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 504 |
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|a Includes bibliographical references and index.
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0 |
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|a Print version record.
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| 520 |
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|a A comprehensive introduction to using modeling and simulation programs in drug discovery and development Biopharmaceutical modeling has become integral to the design and development of new drugs. Influencing key aspects of the development process, including drug substance design, formulation design, and toxicological exposure assessment, biopharmaceutical modeling is now seen as the linchpin to a drug's future success. And while there are a number of commercially available software programs for drug modeling, there has not been a single resource guiding pharmaceutical professionals to the ac.
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| 505 |
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|a Introduction -- Theoretical framework I : solubility -- Theoretical framework II : dissolution -- Theoretical framework III : biological membrane permeation -- Theoretical framework IV : gastrointestinal transit models and integration -- Physiology of gastrointestinal tract and other administration sites in humans and animals -- Drug parameters -- Validation of mechanistic models -- Bioequivalence and biopharmaceutical classification system -- Dose and particle size dependency -- Enabling formulations -- Food effect -- Biopharmaceutical modeling for miscellaneous cases -- Intestinal transporters -- Strategy in drug discovery and development -- Epistemology of biopharmaceutical modeling and good simulation practice.
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| 650 |
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|a Biopharmaceutics.
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| 650 |
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|a Computer simulation.
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| 650 |
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|a Digital computer simulation.
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| 650 |
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|a Pharmacology.
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| 650 |
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|a Pharmaceutical technology.
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| 650 |
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|a Medical personnel.
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| 650 |
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|a Life sciences.
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| 650 |
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|a Physical sciences.
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| 650 |
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|a Methodology.
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| 650 |
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|a Mathematical models.
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| 650 |
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|a simulation.
|2 aat
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| 650 |
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|a pharmacology.
|2 aat
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| 650 |
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7 |
|a biological sciences.
|2 aat
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| 650 |
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7 |
|a physical sciences.
|2 aat
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| 650 |
|
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|a methodology.
|2 aat
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| 650 |
|
7 |
|a mathematical models.
|2 aat
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| 650 |
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7 |
|a MEDICAL
|x Pharmacology.
|2 bisacsh
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| 650 |
|
7 |
|a Physical sciences
|2 fast
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| 650 |
|
7 |
|a Pharmacology
|2 fast
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| 650 |
|
7 |
|a Pharmaceutical technology
|2 fast
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| 650 |
|
7 |
|a Methodology
|2 fast
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| 650 |
|
7 |
|a Medical personnel
|2 fast
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| 650 |
|
7 |
|a Mathematical models
|2 fast
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| 650 |
|
7 |
|a Life sciences
|2 fast
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| 650 |
|
7 |
|a Digital computer simulation
|2 fast
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| 650 |
|
7 |
|a Biopharmaceutics
|2 fast
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| 650 |
|
7 |
|a Computer simulation
|2 fast
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| 650 |
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7 |
|a Health & Biological Sciences.
|2 hilcc
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| 650 |
|
7 |
|a Pharmacy, Therapeutics, & Pharmacology.
|2 hilcc
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| 758 |
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|i has work:
|a Biopharmaceutics modeling and simulations (Text)
|1 https://id.oclc.org/worldcat/entity/E39PCGXdYJGP9fvyTxTr36XDFX
|4 https://id.oclc.org/worldcat/ontology/hasWork
|
| 776 |
0 |
8 |
|i Print version:
|a Sugano, Kiyohiko.
|t Biopharmaceutics modeling and simulations.
|d Hoboken, N.J. : Wiley-Blackwell ; Chichester : John Wiley [distributor], 2012
|z 9781118028681
|w (OCoLC)796278081
|
| 856 |
4 |
0 |
|u https://ebookcentral.proquest.com/lib/holycrosscollege-ebooks/detail.action?docID=875932
|y Click for online access
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| 903 |
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|a EBC-AC
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| 994 |
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|a 92
|b HCD
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