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Regulatory T cells /
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Regulatory T cells / Ren S. Hayashi, editor.
Saved in:
Bibliographic Details
Other Authors:
Hayashi, Ren S.
Format:
eBook
Language:
English
Published:
New York :
Nova Science Publishers,
c2011.
Series:
Cell biology research progress.
Immunology and immune system disorders.
Subjects:
T cells.
Immune response
>
Regulation.
MEDICAL
>
Immunology.
Immune response
>
Regulation
T cells
Online Access:
Click for online access
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Description
Table of Contents
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Table of Contents:
REGULATORY T CELLS
REGULATORY T CELLS
Contents
Preface
T Helper 17 Cells Interplay with CD4+CD25highFoxp3+ Regulatory T cells in Regulating Autoimmune Inflammation
1. Abstract
2. Introduction
3. Comparison of the New Multi-Subset Paradigm to the old Th1-Th2 Paradigm
3.1. Imperfect Th1-Th2 Paradigm
3.2. New CD4+ Th Subsets � Tregs, Th17, Th9, Tfh, IL-10 IFN-Gamma-Secreting CD4+ T cells and CD4+CD28null T Cells
3.2.1. Tregs
3.2.2. Th17
3.2.3. Th9
3.2.4. Tfh
3.2.5. IL-10- IFN-gamma-secreting CD4+ T cells
3.2.6. CD4+CD28null T cells 4. Structural Characters of IL-17 Family Cytokines
5. Th17 Cells, a New Proinflammatory and Autoimmune CD4+ T Cell Subset
6. Wide Spectrum Effects of IL-17 on Various Cell Types and Tissues
6.1. Synovial Stromal Cells
6.2. Fibroblasts
6.3. Endothelial Cells
6.4. Vascular Smooth Muscle Cells (VSMCs)
6.5. Monocytic Cells and Macrophages
6.6. Structural Lung Cells
7. Signaling Pathways Initiated by Binding of IL-17 Cytokines and IL-17 Receptors
7.1. IL-17 Receptor Family
7.2. IL-17 Receptor Complex Components 7.3. IL-17 Receptor Signaling
8. Th17/IL-17-Mediated Inflammations
8.1. Experimental Autoimmune Encephalomyelitis (EAE)/Multiple Sclerosis
8.2. Inflammatory Skin Disease in Mice and Psoriasis in Humans
8.3. Inflammatory Bowel Disease (IBD) [1]
8.4. Experimental Arthritis/Rheumatoid Arthritis [1]
8.5. Atherosclerosis
8.6. Diabetes
9. Protective Roles of IL-17 in Infections
10. Interplay between Th17 Cells and Tregs
10.1. Recent Progress in Characterizing Tregs
10.2. Reciprocally Interconnected Th17 and Tregs10.3. Inhibition of Th17 by Tregs
Conclusion
References
Human CD8 Tregs as Contender in Chronic Persisting Infections
Abstract
Introduction
Treg Subsets, Markers and Plasticity
CD8 Tregs in Human Disease
Mechanism of Suppression by CD8+ Tregs
The CCL4-CCR5 Axis as a New Player in CD8 Treg Mediated Suppression
Evidence for Involvement of Tregs in Chronic Human Infectious Diseases
Human CD4+ Tregs in Infectious Diseases
Mycobacterial infections
Parasitic infections
Other bacterial infections Viral infections
Human CD8+ Tregs in Infectious Diseases
Mycobacterial infections
Viral infections
Antigen Specificity & HLA Restriction of Tregs
Location of Tregs Suggests Significant Role in Containment of Pathogens, but Timing of Treg Activity is Crucial
Tregs in TB Vaccination May Inhibit TB Protection: Lessons for Rational Vaccine Design
Conclusion
Acknowledgments
References
Role of Regulatory t Cells in the Treatment of Multiple Sclerosis
Abstract
1. Introduction
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