Hoppa till innehåll
Library Home
Start Over
Research Databases
E-Journals
Kursböcker
Library Home
Logga in
English
Deutsch
Español
Français
Italiano
日本語
Nederlands
Português
Português (Brasil)
中文(简体)
中文(繁體)
Türkçe
עברית
Gaeilge
Cymraeg
Ελληνικά
Català
Euskara
Русский
Čeština
Suomi
Svenska
polski
Dansk
slovenščina
اللغة العربية
বাংলা
Galego
Tiếng Việt
Hrvatski
हिंदी
Հայերէն
Українська
Språk
Library Catalog
Alla fält
Titel
Upphovsman
Ämne
Signum
ISBN/ISSN
Sök
Avancerad sökning
|
Bläddra
|
Söktips
Osteoblasts :
Hänvisa
Textmeddelande
Skicka per e-post
Skriv ut
Exportera posten
Exportera till: RefWorks
Exportera till: EndNoteWeb
Exportera till: EndNote
Lägg till i favoriter
Permanent länk
Osteoblasts : morphology, functions and clinical implications / Hugo Scheurer, editor.
Sparad:
Bibliografiska uppgifter
Övriga upphovsmän:
Scheurer, Hugo
Materialtyp:
E-bok
Språk:
English
Publicerad:
New York :
Nova Science Publishers,
[2013]
Serie:
Cell biology research progress.
Muscular system--anatomy, functions, and injuries series.
Ämnen:
Osteoclasts.
Bone resorption.
Bones
>
Diseases.
MEDICAL
>
Physiology.
SCIENCE
>
Life Sciences
>
Human Anatomy & Physiology.
Bone resorption
Bones
>
Diseases
Osteoclasts
Länkar:
Click for online access
Beståndsuppgifter
Beskrivning
Innehållsförteckning
Liknande verk
Katalogiseringsuppgifter
Innehållsförteckning:
Intro
OSTEOBLASTS
OSTEOBLASTS
Contents
Preface
Osteoblasts under Mechanical Strain
Abstract
Abbreviations
1. Introduction
1.1. Bone Tissue Cellular Structure
1.2. Osteoblasts
1.2.1. Osteoblast Origin and Life Cycle
1.2.2. Osteoblast Function
1.2.3. Growth Factor and Hormone Effects on Osteoblasts
1.3. Runx2 Transcription Factor in Bone Biology
1.3.1. Runx2 in Osteoblast Differentiation
1.3.2. Structure of Runx2 Gene
1.3.3. Runx2 Expression
2. Bone Remodeling
2.1. Regulation of Bone Remodeling
2.2. The Role of the RANK / RANKL / OPG System in Bone Remodeling
2.3. Bone Remodeling Pathophysiology
3. Mechanotransduction
3.1. Bone Remodeling and Mechanotransduction
3.2. Runx2 in Mechanotransduction
3.3. Nuclear Factor Î#x9A;appa B (NF-κÎ#x92;) Transcription Factor in Mechanotransduction
3.4. Polycystins in Mechanotransduction
3.5. Model Systems for the Study of Mechanotransduction in Osteoblasts
3.6. The Role of Mechanotransduction in Bone Disease
3.7. Mechanical Stimulation as a Therapeutic Strategy against Bone Disease
Conclusion
References
From Stem Cells to Osteoblast: Therapeutic Potential for Bone Tissue Engineering
Abstract
Introduction
Mesenchymal Stem Cells
Differentiation of MSC into Osteoblast
Role of Growth Factors and Transcription Factors in Osteoblast Differentiation
Role of Transcription Factor in Differentiation of Osteoblast
Scaffolds
Natural Scaffolds: Extracellular Matrix
Glycosaminoglycans (GAGs)
Chitosan Scaffold
Tripolymer Scaffolds
References
Osteoblast Functions and their Role in Skeletal Bone Diseases
Abstract
Introduction
Osteoblast Lineage and Differentiation
Transcription Factors, Signaling Proteins and Osteoblast Differentiation
Osteoblast Migration
Osteoblasts and Bone Diseases.
Osteoporosis
Osteoarthritis
Osteogenesis Imperfecta
Van Buchem Disease and Sclerosteosis
Oculodentodigital Dysplasia
Camurati-Engelmann Disease
Cleidocranial Dysplaysia
Osteoblastic Bone Metastasis
Acknowledgment
References
Osteoblast Differentiation and Related Diseases
Abstract
Introduction
A. Transcription Factors Regulating Osteoblast Differentiation
RUNX2
TWIST1
MSX1 and MSX2
SP7/Osterix
β-Catenin
ATF4
FoxO1
B. Diseases Associated with Osteogenic Transcription Factors
Cleidocranial Dysplasia (CCD)
Saethre Chotzen Syndrome (SCS)
Boston-Type Craniosynostosis
Non-Collagenous Osteogenesis Imperfecta Caused by SP7/OSX Mutation
Coffin-Lowry Syndrome (CLS)
Neurofibromatosis Type I
Conclusion
References
BMP and Osteoblastogenesis Inhibitors
Abstract
Bone Morphogenetic Proteins
BMP-Smad Signaling
Extracellular Inhibitor
Cytomembrane Inhibitors
Intracellular Inhibitors
Nuclear Inhibitors, Which Interact with Runx2 or Osx
MicroRNAs
Prospect for Future Therapy
References
The Effect of Molecular and Biochemical Differentiation Agentson Bone Formation
Abstract
Introduction
Osteoblast Differentiation and Inducer Materials
Standard Medium for Osteogenic Cultures
Medium Supplements
Ascorbic Acid
1. The Effect of Ascorobic Acid on Osteoclast Formation
2. The Effect of Ascorbic Acid on Osteoblast Formation
B-Glycerophosphate (BGP)
Dexamethasone (Dex)
Vitamin D3
Bone Morphogenic Protein 2(BMP-2)
Collagen I and Vetronectin
Conclusion and Further Remarks
References
Evaluation of Characteristics of Osteoblasts and Factors Relatedto Osteoblastic Differentiation and Mineralization
Abstract
Introduction
Characteristics of Osteblast
Bone Morphogenetic Protein (BMP)
Various Agents.
Laboratory Experiments
(1) Cellular Proliferation
(2) Alkaline Phosphatase Activity Assays (ALP)
(3) Mineralization Assay
Conclusion
References
Index.
Liknande verk
Osteoclasts : morphology, functions and clinical implications
Publicerad: (2012)
Current topics in bone biology
Publicerad: (2005)
The physiological basis of metabolic bone disease
Publicerad: (2014)
The growth plate
Publicerad: (2002)
Bones : structure and mechanics
av: Currey, John D.
Publicerad: (2002)