Biophysical methods for biotherapeutics : discovery and development applications

Biophysical methods for biotherapeutics : discovery and development applications / edited by Dr. Tapan K. Das.

With a focus on practical applications of biophysical techniques, Biophysical Methods for Biotherapeutics helps formulation and analytical scientists in pharma and biotech better understand and use biophysical methods. Author Tapan K. Das links fundamental biophysics to the process of biopharmaceuti...

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Bibliographic Details
Other Authors: Das, Tapan K. (Editor)
Format: eBook
Language:English
Published: Hoboken, New Jersey : Wiley, [2014]
Subjects:
Biopharmaceutics > Methodology.
MEDICAL > Pharmacology.
Biopharmaceutics
Livres électroniques.
Methods (Music)
Online Access:Click for online access
Table of Contents:
  • Biophysical methods applied in early discovery of a biotherapeutic : case study of an EGFR-IGF1R bispecific adnectin / Michael L. Doyle, James W. Bryson, Virginie Lafont, Zheng Lin, Paul E. Morin, Lumelle A. Schneeweis, Aaron P. Yamniuk, and Joseph Yanchunas Jr
  • X-ray crystallography for biotherapeutics / Glen Spraggon
  • Solubility and early assessment of stability for protein therapeutics / Sheng-Jiun Wu, Gary L. Gilliland and Yiqing Feng
  • Biophysical and structural characterization needed prior to proof of concept / Angela W. Blake-Haskins, Yen-Huei Lin, Zhuchun Wu, Melissa D. Perkins, Thomas M. Spitznagel
  • Nucleation, aggregation, and conformational distortion / Christopher J. Roberts
  • Utilization of chemical labeling and mass spectrometry for the biophysical characterization of biopharmaceuticals / Justin B. Sperry and Lisa M. Jones
  • Application of biophysical and high throughput methods in the preformulation of therapeutic proteins? : facts and fictions / Ahmad M. Abdul-Fattah and Hanns-Christian Mahler
  • Bioanalytical methods and immunogenicity assays / Bonita Rup, Corinna Krinos-Fiorotti, Boris Gorovits, Hendrik Neubert
  • Structures and dynamics of proteins probed by UV resonance raman spectroscopy / Brian S. Leigh, Diana E. Schlamadinger, and Judy E. Kim
  • Freezing and drying-induced micro-/nanoheterogeneity in biological solutions / Alptekin Aksan, Vishard Ragoonanan, and Carol Hirschmugl
  • Late stage product characterization : applications in formulation, process and manufacturing development / Christine P. Chan and Li Shi
  • Biophysical analyses suitable for chemistry, manufacturing and control sections of the biological license application (BLA) / Zahra Shahrokh, Nazila Salamat-Miller, John J. Thomas.

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