Immunology : a short course

Immunology : a short course / Richard Coico, Geoffrey Sunshine.

Immunology: A Short Course, Seventh Edition introduces allthe critical topics of modern immunology in a clear and succinct yet comprehensive fashion. The authors offer uniquely-balanced coverage of classical and contemporary approaches and basic and clinical aspects. The strength of Immunology: A Sh...

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Bibliographic Details
Main Authors: Coico, Richard (Author), Sunshine, Geoffrey (Author)
Format: eBook
Language:English
Published: Chichester, West Sussex, UK ; Hoboken, NJ : John Wiley & Sons Inc., 2015.
Edition:Seventh edition.
Subjects:
Immunology.
Immune system.
Immunity.
Immunologic diseases.
HEALTH & FITNESS > Diseases > General.
MEDICAL > Clinical Medicine.
MEDICAL > Diseases.
MEDICAL > Evidence-Based Medicine.
MEDICAL > Internal Medicine.
Immunologic diseases
Immunity
Immune system
Immunology
Online Access:Click for online access

MARC

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100 1 |a Coico, Richard,  |e author. 
245 1 0 |a Immunology :  |b a short course /  |c Richard Coico, Geoffrey Sunshine. 
250 |a Seventh edition. 
264 1 |a Chichester, West Sussex, UK ;  |a Hoboken, NJ :  |b John Wiley & Sons Inc.,  |c 2015. 
300 |a 1 online resource (xxiii, 406 pages) :  |b illustrations (chiefly color) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
505 0 |6 880-01  |a Overview of the immune system -- Innate immunity -- Adaptive immunity -- Immunogens and antigens -- Antibody structure and function -- Antigen-antobody interactions, immune assays, and experimental systems -- The genetic basis of antibody structure -- Biology of the B lymphocyte -- How T cells recognize antigen : the role of the major histocompatibility complex -- Biology of the T lymphocyte -- Activation and function of T cells -- Cytokines -- Tolerance and autoimmunity -- Complement -- Hypersensitivity : type I -- Hypersensitivity : types II and III -- Hypersensitivity : type IV -- Immunodeficiency disorders and neoplasias of the lymphoid system -- Transplantation -- Tumor immunology -- Resistance and immununization to infectious diseases. 
588 0 |a Online resource; title from resource home page (ebrary, viewed November 24, 2015). 
520 |a Immunology: A Short Course, Seventh Edition introduces allthe critical topics of modern immunology in a clear and succinct yet comprehensive fashion. The authors offer uniquely-balanced coverage of classical and contemporary approaches and basic and clinical aspects. The strength of Immunology: A Short Course is in providing a complete review of modern immunology without the burden of excessive data or theoretical discussions. Each chapter is divided into short, self-contained units that address key topics, illustrated by uniformly drawn, full-color illustrations and photographs. 
650 0 |a Immunology. 
650 0 |a Immune system. 
650 0 |a Immunity. 
650 0 |a Immunologic diseases. 
650 7 |a HEALTH & FITNESS  |x Diseases  |x General.  |2 bisacsh 
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650 7 |a MEDICAL  |x Diseases.  |2 bisacsh 
650 7 |a MEDICAL  |x Evidence-Based Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Internal Medicine.  |2 bisacsh 
650 7 |a Immunologic diseases  |2 fast 
650 7 |a Immunity  |2 fast 
650 7 |a Immune system  |2 fast 
650 7 |a Immunology  |2 fast 
700 1 |a Sunshine, Geoffrey,  |e author. 
776 0 8 |i Print version:  |a Coico, Richard.  |t Immunology.  |b Seventh edition.  |d Chichester, West Sussex, UK ; Hoboken, NJ : John Wiley & Sons Inc., 2015  |z 9781118396919  |w (DLC) 2014023101 
856 4 0 |u https://ebookcentral.proquest.com/lib/holycrosscollege-ebooks/detail.action?docID=7103605  |y Click for online access 
880 0 0 |6 505-00/(S  |g Machine generated contents note:  |t Introduction, --  |t Innate and Adaptive Immunity, --  |t Innate Immunity, --  |t Adaptive Immunity, --  |t Clonal Selection Theory, --  |t Active, Passive, and Adoptive Immunization, --  |t Major Characteristics of the Adaptive Immune Response, --  |t Cells Involved in the Adaptive Immune Response, --  |t Humoral and Cellular Immunity, --  |t Humoral Immunity, --  |t Cell-Mediated Immunity, --  |t Generation of Diversity in the Immune Response, --  |t Benefits of Immunology, --  |t Damaging Effects of the Immune Response, --  |t Future of Immunology, --  |t Short Course Begins Here, --  |t References and Bibliography --  |t Introduction, --  |t Physical and Chemical Barriers of Innate Immunity, --  |t Origin, Differentiation, and Characterization of Cells of the Innate Immune System, --  |t Pattern Recognition: The Hallmark of Innate Immune Responses, --  |t Pattern Recognition Receptors, --  |t Complement, --  |t Intracellular and Extracellular Killing of Microorganisms, --  |t Inflammation, --  |t Hallmark Signs of Inflammation, --  |t Localized Inflammatory Responses, --  |t Chronic Inflammation, --  |t Fever, --  |t References and Bibliography, --  |t Review Questions, --  |t Answers to Review Questions, --  |t Cells and Organs Involved in Adaptive Immunity, --  |t Lymphatic Organs, --  |t Lymphocyte Migration and Recirculation, --  |t Fate of Antigen after Penetration, --  |t Frequency of Antigen-Specific Naïve Lymphocytes, --  |t Interrelationship between Innate and Adaptive Immunity, --  |t Review Questions, --  |t Answers to Review Questions, --  |t Introduction, --  |t Requirements for Immunogenicity, --  |t Foreignness, --  |t High Molecular Weight, --  |t Chemical Complexity, --  |t Degradability, --  |t Haptens, --  |t Further Requirements for Immunogenicity, --  |t Primary and Secondary Responses, --  |t Antigenicity and Antigen-Binding Site, --  |t Epitopes Recognized by B Cells and T Cells, --  |t Major Classes of Antigens, --  |t Binding of Antigen with Antigen-Specific Antibodies or T Cells, --  |t Cross-Reactivity, --  |t Adjuvants, --  |t References and Bibliography, --  |t Review Questions, --  |t Answers to Review Questions, --  |t Introduction, --  |t Isolation and Characterization of Immunoglobulins, --  |t Structure of Light and Heavy Chains, --  |t Domains, --  |t Hinge Region, --  |t Variable Region, --  |t Immunoglobulin Variants, --  |t Isotypes, --  |t Allotypes, --  |t Idiotypes, --  |t Structural Features of IgG, --  |t Biologic Properties of IgG, --  |t Agglutination and Formation of Precipitate, --  |t Passage through the Placenta and Absorption in Neonates, --  |t Opsonization, --  |t Antibody-Dependent Cell-Mediated Cytotoxicity, --  |t Activation of Complement, --  |t Neutralization of Toxins, --  |t Immobilization of Bacteria, --  |t Neutralization of Viruses, --  |t Structural Features of IgM, --  |t Biologic Properties of IgM, --  |t Complement Fixation, --  |t Neonatal Immunity and First Line of Humoral Defense, --  |t Agglutination, --  |t Isohemagglutinins, --  |t Structural and Biologic Properties of IgA, --  |t Biologic Properties of IgA, --  |t Role in Mucosal Infections, --  |t Bactericidal Activity, --  |t Antiviral Activity, --  |t Structural and Biologic Properties of IgD, --  |t Structural and Biologic Properties of IgE, --  |t Importance of IgE in Parasitic Infections and Hypersensitivity Reactions, --  |t Kinetics of the Antibody Response Following Immunization, --  |t Primary Response, --  |t Secondary Response, --  |t Immunoglobulin Superfamily, --  |t References and Bibliography, --  |t Review Questions, --  |t Answers to Review Questions, --  |t Introduction, --  |t Antigen-Antibody Interactions, --  |t Primary Interactions between Antibody and Antigen, --  |t Association Constant, --  |t Affinity and Avidity, --  |t Secondary Interactions between Antibody and Antigen, --  |t Agglutination Reactions, --  |t Precipitation Reactions, --  |t Immunoassays, --  |t Direct-Binding Immunoassays, --  |t Solid-Phase Immunoassays, --  |t Immunofluorescence, --  |t Direct Immunofluorescence, --  |t Indirect Immunofluorescence, --  |t Flow Cytometry, --  |t Immunoabsorption and Immunoadsorption, --  |t Cellular Assays, --  |t Assays of Lymphocyte Function, --  |t B-Cell and T-Cell Proliferation Assays, --  |t Antibody Production by B Cells, --  |t Effector Cell Assays for T Cells and Natural Killer Cells, --  |t Cell Culture, --  |t Primary Cell Cultures and Cloned Lymphoid Cell Lines, --  |t B-Cell Hybridomas and Monoclonal Antibodies, --  |t T-Cell Hybridomas, --  |t Genetically Engineered Molecules and Receptors, --  |t Experimental Animal Models, --  |t Inbred Strains, --  |t Adoptive Transfer, --  |t SCID Mice, --  |t Thymectomized and Congenitally Athymic (Nude) Mice, --  |t Transgenic Mice and Gene Targeting, --  |t Transgenic Mice, --  |t Knockout and Knock-in Mice, --  |t Analysis of Gene Expression, --  |t Microarrays to Assess Gene Expression, --  |t References and Bibliography, --  |t Review Questions, --  |t Answers to Review Questions, --  |t Introduction, --  |t Brief Review of Nonimmunoglobulin Gene Structure and Gene Expression, --  |t Genetic Events in Synthesis of Ig Chains, --  |t Organization and Rearrangement of Light-Chain Genes, --  |t K-Chain Synthesis, --  |t λ-Chain Synthesis, --  |t Organization and Rearrangement of Heavy-Chain Genes, --  |t Allelic Exclusion and the Regulation of Ig Gene Expression, --  |t Class or Isotype Switching, --  |t Generation of Antibody Diversity, --  |t Presence of Multiple V Genes in the Germline, --  |t VJ and VDJ Combinatorial Association, --  |t Random Assortment of H and L Chains, --  |t Junctional Diversity, --  |t Somatic Hypermutation, --  |t Somatic Gene Conversion, --  |t Role of Activation-Induced Cytidine Deaminase in Generating Antibody Diversity, --  |t References and Bibliography, --  |t Review Questions, --  |t Answers to Review Questions, --  |t Introduction, --  |t Development of B Lymphocytes, --  |t Overview, --  |t Sites of Early B-Cell Differentiation, --  |t Pro-B and Pre-B Cells: First Ig Rearrangements, --  |t Immature B Cells, --  |t Transitional B cells, --  |t Mature B Cells, --  |t Plasma Cells, --  |t Memory B Cells, --  |t Sites of Antibody Synthesis, --  |t Interaction of Antigen, B Cells, and Helper T Cells in the Lymph Node, --  |t Events in the Germinal Center, --  |t Antibody Synthesis in Mucosal Tissue, --  |t Thymus-Independent Antibody Responses, --  |t B-Cell Membrane Proteins, --  |t Stage-Specific Markers, --  |t Antigen-Binding Molecules: Membrane Immunoglobulin, --  |t Signal Transduction Molecules Associated with Membrane Immunoglobulin, --  |t Molecules Involved in T-B Cell Interactions, --  |t Homing, --  |t Intracellular Signaling in B Cells, --  |t References and Bibliography, --  |t Review Questions, --  |t Answers to Review Questions, --  |t Introduction, --  |t How the MHC Got Its Name, --  |t MHC Role in Antigen Presentation, --  |t Different MHC Molecules Are Expressed by Distinct Host Cells and Interact with Different Sets of T Cells, --  |t MHC Class I, --  |t MHC Class II, --  |t Variability of MHC Class I and MHC Class II Molecules, --  |t Structure of MHC Class I and Class II Molecules, --  |t MHC Class I, --  |t Structure of MHC Class II Molecules, --  |t Antigen Processing and Presentation: How MHC Molecules Bind Peptides and Create Ligands That Interact with T Cells, --  |t Exogenous Antigens and Generation of MHC Class II-Peptide Complexes, --  |t Endogenous Antigens: Generation of MHC Class I-Peptide Complexes, --  |t Cross-Presentation: Exogenous Antigens Presented in the MHC Class I Pathway, --  |t Which Antigens Trigger Which T-Cell Responses, --  |t MHC Molecules Bind Peptides Derived from Self-Molecules, --  |t Inability to Respond to an Antigen, --  |t Other Types of Antigen That Activate T-Cell Responses, --  |t Superantigens, --  |t Lipids and Glycolipids, --  |t Multiple Antigens Activate γδ Cells, --  |t Genes of the HLA Region, --  |t Nomenclature of Polymorphic MHC Molecules, --  |t Regulation of Expression of MHC Genes, --  |t Codominant Expression, --  |t Coordinate Regulation, --  |t Inheritance of MHC Genes, --  |t MHC in Other Species, --  |t Diversity of MHC Molecules: MHC Association with Resistance and Susceptibility to Disease, --  |t References and Bibliography, --  |t Review Questions, --  |t Answers to Review Questions, --  |t Introduction, --  |t Antigen-Specific T-Cell Receptor, --  |t Molecules That Interact with Antigen, --  |t T-Cell Receptor Complex, --  |t Co-Receptors, --  |t Other Important Molecules Expressed on the T-Cell Surface, --  |t γδ T Cells, --  |t Genes Coding for T-Cell Receptors, --  |t Generation of T-Cell Receptor Diversity, --  |t T-Cell Differentiation in the Thymus, --  |t Thymus as Primary Organ for T-Cell Differentiation, --  |t Key Steps in Thymic Differentiation, --  |t Early T-Cell Receptor Gene Rearrangements: Double-Negative Cells and Splitting Off of γδ T Cells, --  |t Pre-T Cells, --  |t Double-Positive Cells, --  |t Thymic  
880 0 0 |t Selection, --  |t Leaving the Thymus, --  |t Generation of the T-Cell Repertoire, --  |t Characteristics of o --  |t T Cells Emerging from the Thymus, --  |t Further Differentiation of CD4+ and CD8+ T Cells Outside the Thymus, --  |t Differentiation of Other Cell Types in the Thymus, --  |t References and Bibliography, --  |t Review Questions, --  |t Answers to Review Questions, --  |t Introduction, --  |t Two-Signal Model for the Activation of T Cells, --  |t Dendritic Cells Are the Key APC for Naïve T Cells, --  |t Activation of CD4+ T Cells, --  |t Paired Interactions at the Surface of the APC and CD4+ T Cell, --  |t Intracellular Events in CD4+ T-Cell Activation, --  |t Differentiation to Effector Cells and Migration Out of the Lymph Node, --  |t Termination of the Response, --  |t Other Ways to Activate CD4+ T Cells, --  |t CD4+ T-Cell Function, --  |t Cytokine Synthesis, --  |t Major Subsets of Cytokine-Producing CD4+ T Cells, --  |t Cross-Inhibition of CD4+ T-Cell Subsets, --  |t Other Sets of Cytokine-Producing CD4+ T Cells, --  |t Further Points on Cytokine Synthesis, --  |t Help for B Cell in the Response to TD Antigens, --  |t Events in the Germinal Center, --  |t Linked Recognition, --  |t Activation and Function of CD8+ T Cells, --  |t Generation of Effector CD8+ T Cells, 
880 0 0 |6 505-01/(S  |g Contents note continued:  |t CD8+ T-Cell Killing of Target Cells, --  |t MHC Restriction and CD8+ T Cell Killer Function, --  |t Memory T Cells, --  |t Function of Other Subsets of T Cells, --  |t NKT Cells, --  |t γδ T Cells, --  |t Innate Lymphoid Cells, --  |t References and Bibliography, --  |t Review Questions, --  |t Answers to Review Questions, --  |t Introduction, --  |t History of Cytokines, --  |t Pleiotropic and Redundant Properties of Cytokines, --  |t General Properties of Cytokines, --  |t Common Functional Properties, --  |t Common Systemic Activities, --  |t Common Cell Sources and Cascading Events, --  |t Functional Categories of Cytokines, --  |t Cytokines That Facilitate Innate Immune Responses, --  |t Cytokines That Regulate Adaptive Immune Responses, --  |t Cytokines That Induce Differentiation of Distinct T-Cell Lineages, --  |t Cytokines That Inhibit Lineage-Specific T-Cell Differentiation, --  |t Cytokines That Promote Inflammatory Responses, --  |t Cytokines That Affect Leukocyte Movement, --  |t Cytokines That Stimulate Hematopoiesis, --  |t Cytokine Receptors, --  |t Cytokine Receptor Families, --  |t Common Cytokine Receptor Chains, --  |t Cytokine Receptor-Mediated Signal Transduction, --  |t Role of Cytokines and Cytokine Receptors in Disease, --  |t Toxic Shock Syndrome, --  |t Bacterial Septic Shock, --  |t Cancers, --  |t Autoimmunity and Other Immune-Based Diseases, --  |t Therapeutic Exploitation of Cytokines and Cytokine Receptors, --  |t Cytokine Inhibitors/Antagonists, --  |t Reversing Cellular Deficiencies, --  |t Treatment of Immunodeficiencies, --  |t Treatment of Patients with Cancer, Transplanted Organs, and Tissues, and Viral Infections, --  |t Treatment of Allergies and Asthma, --  |t References and Bibliography, --  |t Review Questions, --  |t Answers to Review Questions, --  |t Introduction, --  |t Central Tolerance, --  |t Mechanisms of Central Tolerance: T and B Cells, --  |t Mechanisms of Central Tolerance: B Cells, --  |t Peripheral Tolerance, --  |t Anergy, --  |t Regulatory T Cells, --  |t Fas-FasL Interactions, --  |t Oral Tolerance, --  |t Immune Privilege, --  |t Autoimmunity and Disease, --  |t Genetic Susceptibility, --  |t Environmental Susceptibility, --  |t Drug and Hormonal Triggers of Autoimmunity, --  |t Autoimmune Diseases, --  |t Autoimmune Diseases in Which Antibodies Play a Predominant Role in Mediating Organ Damage, --  |t Autoimmune Diseases in Which T Cells Play a Predominant Role in Organ Damage, --  |t Therapeutic Strategies, --  |t References and Bibliography, --  |t Review Questions, --  |t Answers to Review Questions, --  |t Introduction, --  |t Overview of Complement Activation, --  |t Classical Pathway, --  |t Lectin Pathway, --  |t Alternative Pathway, --  |t Steps Shared by All Pathways: Activation of C3 and C5, --  |t Terminal Pathway, --  |t Regulation of Complement Activity, --  |t Biologic Activities of Complement, --  |t Production of Opsonins, --  |t Production of Anaphylatoxins, --  |t Lysis, --  |t Other Important Complement Functions, --  |t Complement Deficiencies, --  |t References and Bibliography, --  |t Review Questions, --  |t Answers to Review Questions, --  |t Introduction, --  |t Hypersensitivity, --  |t Coombs-Gell Hypersensitivity Designations, --  |t General Characteristics of Allergic Reactions, --  |t Sensitization Phase, --  |t TH2 Cell Dependency of IgE Antibody Production, --  |t Activation Phase, --  |t Effector Phase, --  |t Preformed Mediators, --  |t Newly Synthesized Mediators, --  |t Late-Phase Reaction, --  |t Clinical Aspects of Allergic Reactions, --  |t Allergic Rhinitis, --  |t Food Allergies, --  |t Atopic Dermatitis, --  |t Asthma, --  |t Clinical Tests for Allergies and Clinical Intervention, --  |t Detection, --  |t Intervention, --  |t Protective Role of IgE, --  |t References and Bibliography, --  |t Review Questions, --  |t Answers to Review Questions, --  |t Introduction, --  |t Type II Hypersensitivity, --  |t Complement-Mediated Reactions, --  |t Antibody-Dependent Cell-Mediated Cytotoxicity, --  |t Antibody-Mediated Cellular Dysfunction, --  |t Examples of Type II Hypersensitivity Reactions, --  |t Transfusion Reactions, --  |t Drug-Induced Reactions, --  |t Rhesus Incompatibility Reactions, --  |t Reactions Involving Cell Membrane Receptors, --  |t Reactions Involving Other Cell Membrane Determinants, --  |t Type III Hypersensitivity, --  |t Systemic Immune Complex Disease, --  |t Localized Immune Complex Disease, --  |t References and Bibliography, --  |t Review Questions, --  |t Answers to Review Questions --  |t Introduction, --  |t General Characteristics and Pathophysiology of DTH, --  |t Mechanisms Involved in DTH, --  |t Examples of DTH, --  |t Contact Sensitivity, --  |t Granulomatous Hypersensitivity, --  |t Tuberculin-Type Hypersensitivity, --  |t Allograft Rejection, --  |t Additional Examples of DTH, --  |t Treatment of DTH, --  |t References and Bibliography, --  |t Review Questions, --  |t Answers to Review Questions, --  |t Introduction, --  |t Immunodeficiency Syndromes, --  |t Primary Immunodeficiency Syndromes, --  |t Immunodeficiency Disorders Associated with T Cells and Cell-Mediated Immunity, --  |t B-Cell-Associated or Immunoglobulin-Associated Immunodeficiency Disorders, --  |t Disorders of T-B Interactions, --  |t Phagocytic Dysfunctions, --  |t Natural Killer Cell Deficiency, --  |t Diseases Caused by Abnormalities in the Complement System, --  |t Secondary Immunodeficiency Diseases, --  |t Acquired Immunodeficiency Syndrome, --  |t Initial Description and Epidemiology, --  |t Human Immunodeficiency Virus, --  |t Clinical Course, --  |t Prevention, Control, Diagnosis, and Therapy of HIV Infection, --  |t Neoplasms of Lymphoid System, --  |t B-Cell Neoplasms, --  |t Mature B-Cell Neoplasms, --  |t Plasma Cell Neoplasms, --  |t T-Cell Neoplasms, --  |t Mature T-Cell Neoplasms, --  |t Immunotherapy, --  |t References and Bibliography, --  |t Review Questions, --  |t Answers to Review Questions, --  |t Introduction, --  |t Relationship between Donor and Recipient, --  |t Immune Mechanisms Are Responsible for Allograft Rejection, --  |t Categories of Allograft Rejection, --  |t Hyperacute Rejection, --  |t Acute Rejection, --  |t Chronic Rejection, --  |t Role of MHC Molecules in Allograft Rejection, --  |t Mechanisms of Alloantigen Recognition by T Cells, --  |t Role of T Cell Lineages and Cytokines in Allograft Rejection, --  |t Laboratory Tests Used in Tissue Typing, --  |t Prolongation of Allograft Survival: Immunosuppresive Therapy, --  |t Anti-Inflammatory Agents, --  |t Cytotoxic Drugs, --  |t Agents That Interfere with Cytokine Production and Signaling, --  |t Immunosuppressive Antibody Therapy, --  |t New Immunosuppressive Strategies and Frontiers, --  |t Hematopoietic Stem Cell Transplantation, --  |t Graft-versus-Host Disease, --  |t Xenogeneic Transplantation, --  |t Fetus: A Tolerated Allograft, --  |t References and Bibliography, --  |t Review Questions, --  |t Answers to Review Questions, --  |t Introduction, --  |t Tumor Antigens, --  |t Categories of Tumor Antigens, --  |t Normal Cellular Gene Products, --  |t Mutant Cellular Gene Products, --  |t Tumor Antigens Encoded by Oncogenes, --  |t Immunologic Factors Influencing the Incidence of Cancer, --  |t Effector Mechanisms in Tumor Immunity, --  |t B-Cell Responses to Tumors, --  |t Destruction of Tumor Cells by Opsonization and Phagocytosis, --  |t Antibody-Mediated Loss of Adhesive Properties of Tumor Cells, --  |t Cell-Mediated Responses to Tumor Cells, --  |t Destruction of Tumor Cells by T Lymphocytes, --  |t Antibody-Dependent Cell-Mediated Cytotoxicity, --  |t Destruction of Tumor by NK Cells, NIC/T Cells, and Cytokine-Activated Killer Cells, --  |t Destruction of Tumor Cells by Activated Macrophages and Neutrophils, --  |t Cytokines, --  |t Limitations of the Effectiveness of the Immune Response against Tumors, --  |t Immunodiagnosis, --  |t Detection of Myeloma Proteins Produced by Plasma Cell Tumors, --  |t Detection of α-Fetoprotein, --  |t Carcinoembryonic Antigen, --  |t Detection of Prostate-Specific Antigen, --  |t Cancer Antigen-125, --  |t Tumor Immunoprophylaxis, --  |t Immunotherapy, --  |t Other Immunotherapeutic Strategies in Cancer, --  |t References and Bibliography, --  |t Review Questions, --  |t Answers to Review Questions, --  |t Introduction, --  |t Host Defense against the Various Classes of Microbial Pathogens, --  |t Immunity to Viruses, --  |t Immunity to Bacteria, --  |t Immunity to Parasites, --  |t Immunity to Fungi, --  |t Mechanisms by Which Pathogens Evade the Immune Response, --  |t Encapsulated Bacteria, --  |t Toxins, --  |t Superantigens, --  |t Antigenic Variation, --  |t Intracellular Survival, --  |t Suppression of the Immune System, --  |t Extracellular Enzymes, --  |t Expression of Antibody-Binding Proteins, --  |t Principles of Immunization, --  |t Objectives of Immunization, --  |t Active Immunizations, --  |t Recommended Immunizations, --  |t Use of Vaccines in Selected Populations, --  |t Basic Mechanisms of Protection, --  |t Significance of  
880 0 0 |t the Primary and Secondary Responses, --  |t Age and Timing of Immunizations, --  |t Vaccine Precautions, --  |t Site of Administration of Antigen, --  |t Hazards, --  |t Recent Approaches to Production of Vaccines, --  |t Vaccines Produced by Recombinant DNA, --  |t Conjugated Polysaccharides, --  |t Synthetic Peptide Vaccines, --  |t Virus-Carrier Vaccine, --  |t Bacterium-Carrier Vaccine, --  |t DNA Vaccines, --  |t Toxoids, --  |t Passive Immunization, --  |t Passive Immunization through Placental Antibody Transfer, --  |t Passive Immunization via Colostrum, --  |t Passive Antibody Therapy and Serum Therapy, --  |t Monoclonal and Polyclonal Preparations, --  |t Preparation and Properties of Human Immune Serum Globulin, --  |t Indications for the Use of Immune Globulin, --  |t Precautions on the Uses of Human Immune Serum Globulin Therapy, --  |t Colony-Stimulating Factors, --  |t References and Bibliography, --  |t Review Questions, --  |t Answers to Review Questions. 
903 |a EBC-AC 
994 |a 92  |b HCD 

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