Development of Medications for the Treatment of Opiate and Cocaine Addictions : Issues for the Government and Private Sector.

Development of Medications for the Treatment of Opiate and Cocaine Addictions : Issues for the Government and Private Sector.

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Bibliographic Details
Main Author: National Institute on Drug Abuse, Institute of Medicine Staff
Other Authors: Fulco, Carolyn E., Liverman, Catharyn T.
Format: eBook
Language:English
Published: Washington : National Academies Press, 1900.
Subjects:
Drug addiction > Treatment.
Cocaine abuse > Treatment.
Substance abuse > Treatment.
Cocaine abuse > Treatment
Drug addiction > Treatment
Substance abuse > Treatment
Online Access:Click for online access
Table of Contents:
  • ""Development of Medications for the Treatment of Opiate and Cocaine Addictions: Issues for the Government and Private Sector""; ""Copyright""; ""Acknowledgments""; ""Preface""; ""Note to the Reader""; ""Contents""; ""Executive Summary""; ""STATE OF THE SCIENTIFIC KNOWLEDGE ON ADDICTION""; ""NIDA'S MEDICATIONS DEVELOPMENT DIVISION""; ""EFFECTIVENESS OF TREATMENT""; ""TREATMENT FINANCING""; ""TRAINING AND EDUCATION""; ""FEDERAL REGULATORY ISSUES""; ""Food and Drug Administration""; ""Drug Enforcement Administration""; ""STATE REGULATORY ISSUES""; ""Interim Actions""; ""Long-Term Actions""
  • ""MARKET OBSTACLES AND CREATING INCENTIVES""""Size of the Market""; ""Drug Pricing and Intellectual Property Rights""; ""Societal Stigma""; ""NEED FOR FEDERAL LEADERSHIP""; ""CONCLUSIONS""; ""OPTIONS FOR FURTHER CONSIDERATION""; ""REFERENCES""; ""1 Introduction""; ""PUBLIC-HEALTH REPERCUSSIONS OF ILLICIT DRUG USE""; ""Health Consequences: Violence""; ""Health Consequences: AIDS""; ""Health Consequences: Tuberculosis""; ""Health Consequences: Drug-exposed Infants""; ""ECONOMIC COSTS OF ILLICIT DRUG USE TO SOCIETY""; ""EXTENT OF ILLICIT DRUG USE""; ""ROLE OF PHARMACOTHERAPY""; ""REFERENCES""
  • ""2 Overview of the State of Scientific Knowledge Concerning Drug Addiction""""CONCEPTS OF DRUG ADDICTION""; ""BIOLOGICAL CORRELATES AND PSYCHOPHARMACOLOGY OF ADDICTION""; ""Opiate Addiction""; ""Cocaine Addiction""; ""MDD AND STRATEGIES FOR THE DISCOVERY OF A COCAINE MEDICATION: DESCRIPTION AND CRITICAL ANALYSIS""; ""Introduction""; ""Source of Compounds""; ""Medication Preclinical Screening""; ""In Vitro Screenâ€?Receptors and Mechanisms of Action""; ""In Vivo Screenâ€?Behavioral Tests""; ""Specific Conclusions and Recommendations for the MDD""; ""Clinical Trials""
  • ""Human Behavioral Models""""CONCLUSIONS AND RECOMMENDATIONS""; ""REFERENCES""; ""3 Assessment of the Medications Development Division""; ""STRUCTURE AND FUNCTIONS OF THE MEDICATIONS DEVELOPMENT DIVISION""; ""Mission and History""; ""Research Focus on Opiates and Cocaine""; ""Program Objectives""; ""Organizational Structure""; ""Budget Process""; ""Resources and Funding Instruments""; ""Types of Grants and Contracts""; ""Interagency Agreements""; ""CRADAs""; ""Screening Agreements""; ""Training""; ""RELATIONSHIPS WITH OTHER FEDERAL AGENCIES AND THE PRIVATE SECTOR""
  • ""Food and Drug Administration""""Drug Enforcement Administration""; ""Office of Protection from Research Risks""; ""Pharmaceutical Industry""; ""ASSESSMENT OF THE MEDICATIONS DEVELOPMENT DIVISION""; ""Staff and Resources""; ""Drug-Discovery Programs""; ""Clinical Trials""; ""Clinical-Research Training""; ""Relationships with Regulatory Agencies""; ""Interaction with the Private Sector""; ""SUMMARY""; ""CONCLUSIONS AND RECOMMENDATIONS""; ""REFERENCES""; ""4 Treatment Setting and Effectiveness""; ""TREATMENT SETTING""; ""Opiate Addiction""; ""Cocaine Addiction""

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