Artificial Heart : Prototypes, Policies, and Patients.

Artificial Heart : Prototypes, Policies, and Patients.

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Bibliographic Details
Main Author: Hogness, John R.
Other Authors: VanAntwerp, Malin, P, Committee Staff to Evaluate the Artificial Heart
Format: eBook
Language:English
Published: Washington : National Academies Press, 1991.
Subjects:
National Heart and Lung Institute. > Artificial Heart Program.
National Heart and Lung Institute. > Artificial Heart Program
Heart, Artificial.
Heart, Artificial
Online Access:Click for online access
Table of Contents:
  • The Artificial Heart
  • Copyright
  • Acknowledgments
  • Preface
  • Contents
  • The Artificial Heart
  • Executive Summary
  • TECHNOLOGICAL PROGRESS AND BARRIERS
  • MAKING DECISIONS ABOUT FUTURE RESEARCH
  • CLINICAL EFFECTIVENESS
  • PROJECTED PATIENT NEED
  • HEALTH-RELATED QUALITY OF LIFE
  • COST-EFFECTIVENESS
  • APPROPRIATENESS OF USE OF MECHANICAL CIRCULATORY SUPPORT
  • PATIENT ACCESS TO MCSSS
  • ETHICAL CONSIDERATIONS
  • RESEARCH AND DEVELOPMENT POLICY ISSUES
  • REGULATORY DECISIONS ABOUT NEW TECHNOLOGIES
  • DEVELOPMENT OF TOTAL ARTIFICIAL HEARTS
  • CONTINUED DEVELOPMENT OF VENTRICULAR ASSIST DEVICESADDITIONAL RESEARCH
  • USING THIS REPORT
  • 1 The Artificial Heart Program: Current Status and History
  • END-STAGE HEART DISEASE
  • HOW LONG-TERM IMPLANTABLE DEVICES COULD HELP
  • Ventricular Assist Devices
  • Total Artificial Hearts
  • Temporary Circulatory Support
  • THE ARTIFICIAL HEART PROGRAM
  • THE INSTITUTE OF MEDICINE STUDY
  • REFERENCES
  • 2 Total Artificial Hearts: Technological Potential and Research and Development Costs
  • TEMPORARY CIRCULATORY SUPPORT
  • LONG-TERM DEVICES UNDER DEVELOPMENT
  • ENGINEERING ASSESSMENT OF MECHANICAL CIRCULATORY SUPPORT DEVICESMechanical Failure
  • Device Components as Limiting Factors
  • Device Longevity
  • CLINICAL COMPLICATIONS WITH MECHANICAL CIRCULATORY SUPPORT DEVICES
  • ALTERNATIVE TECHNOLOGIES FOR PREVENTING AND TREATING END-STAGE HEART DISEASE
  • Conventional Medical Treatment
  • Other Cardiac Assistance Technologies
  • Heart Transplantation
  • SUMMARY OF THE CURRENT AND FUTURE STATE OF TOTAL ARTIFICIAL HEART TECHNOLOGY
  • RESEARCH AND DEVELOPMENT COSTS OF TOTAL ARTIFICIAL HEARTS
  • Stages of the Innovative Process
  • Support for the Artificial Heart ProgramConsidering the Costs of Research and Development to Industry
  • CONCLUSIONS
  • REFERENCES
  • 3 Decisions for Future Research and Development
  • ALLOCATING RESEARCH FUNDS
  • JUDGMENT-BASED DECISION MAKING
  • QUANTIFIED AIDS TO DECISION MAKING
  • Cost-Effectiveness Analysis
  • Application of Methods
  • DECISION-MAKING AIDS SUGGESTED BY THE COMMITTEE
  • Explicit Criteria for Allocation of Funds
  • The More Important Criteria
  • Important Criteria
  • Less Important Criteria
  • Application of Decision Criteria
  • A NOTE ABOUT INDUSTRY RESEARCH AND DEVELOPMENT DECISIONSSUMMARY AND CONCLUSIONS
  • REFERENCES
  • 4 Clinical Effectiveness and Need For Long-Term Circulatory Support
  • ESTIMATING THE NEED FOR LONG-TERM SUPPORT
  • FROM TEMPORARY TO LONG-TERM USE
  • PROJECTING DEVICE RELIABILITY AND EFFECTIVENESS
  • RELATING CLINICAL EFFECTIVENESS AND DEVICE USE
  • The Role of Comorbidities
  • OTHER INFLUENCES ON THE USE OF CIRCULATORY SUPPORT DEVICES
  • The Impact of Other Heart Disease Treatment Technologies
  • Quality-of-Life Determinants

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