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Methyl Bromide Risk Characteri...
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Methyl Bromide Risk Characterization in California.
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Bibliographic Details
Main Author:
Staff, National Research Council
Format:
eBook
Language:
English
Published:
Washington :
National Academies Press,
2000.
Series:
Compass series Methyl bromide risk characterization in California
Subjects:
Bromomethane
>
Toxicology
>
California.
Health risk assessment
>
California.
Pesticides.
Toxicology.
Pollution.
Agricultural chemicals.
Pharmacology.
Life sciences.
Public health.
Physical sciences.
Medical care.
pesticide.
toxicology.
pharmacology.
biological sciences.
public health.
physical sciences.
Toxicology
Public health
Pollution
Physical sciences
Pharmacology
Pesticides
Medical care
Life sciences
Agricultural chemicals
Bromomethane
>
Toxicology
Health risk assessment
North America.
North America
California
Online Access:
Click for online access
Holdings
Description
Table of Contents
Similar Items
Staff View
Table of Contents:
METHYL BROMIDE RISK CHARACTERIZATION IN CALIFORNIA
Copyright
Preface
Contents
Executive Summary
THE SUBCOMMITTEE'S TASK
THE SUBCOMMITTEE'S EVALUATION
Toxicology
Recommendations
Exposure
Recommendations
Risk Characterization
Recommendations
1 Introduction
BACKGROUND
CALIFORNIA REGULATIONS
THE SUBCOMMITTEE'S TASK
ORGANIZATION OF THE REPORT
2 Toxicology and Hazard Identification
PHARMACOKINETICS
GENOTOXICITY
ACUTE TOXICITY
SUBCHRONIC TOXICITY
CHRONIC INHALATION AND ONCOGENICITY
REPRODUCTIVE TOXICITYDEVELOPMENTAL TOXICITY
NEUROTOXICITY
SELECTION OF CRITICAL EFFECTS FOR ACUTE TOXICITY
3 Exposure Assessment
BACKGROUND
LIKELY EXPOSURE SCENARIOS
QUALITY OF DATA AVAILABLE FOR CHARACTERIZING EXPOSURES
Analytical Methods
Representativeness of Available Exposure Measurements
Appropriateness of Normalizing Assumptions for Different Application Rates
Appropriateness of Exposure-Duration Assumptions
ACCURACY AND APPROPRIATENESS OF AVAILABLE MODELING TOOLS
Exposure Estimates Based on Modeling
Exposure of Residents in a Fumigated HouseExposure of Residents Downwind from Soil Fumigations
SUMMARY
4 Risk Characterization
RISK CHARACTERIZATION GOALS
HAZARD IDENTIFICATION
Acute Toxicity Database
Subchronic Toxicity Database
Chronic Toxicity Database
Developmental Neurotoxicity
EXPOSURE ASSESSMENT
Appropriateness of Acute-Exposure Definition
Subchronic Exposure
Chronic Exposure
MARGIN-OF-EXPOSURE ANALYSIS
Categories with More than Two Data Points
Categories with One or Two Data Points
UNCERTAINTY ISSUESDerivation of Reference Concentrations
Sensitive Subpopulations
Multiple Exposures
SUMMARY
5 Conclusions and Recommendations
TOXICOLOGICAL INFORMATION
Conclusions
Recommendations
EXPOSURE ASSESSMENT
Conclusions
Recommendations
RISK CHARACTERIZATION
Conclusions
Recommendations
References
Appendix A Biographical Information on the Subcommittee for the Review of the Risk Assessment of Methyl Bromide
Appendix B Public Access Materials
Appendix C Calculation of Air Exchange Rates
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