Practical transfusion medicine

Practical transfusion medicine / edited by Michael F. Murphy, David J. Roberts, Mark H. Yazer.

The fifth edition of this practical textbook on transfusion medicine has been thoroughly revised with the latest in scientific and technological developments and edited by a leading team of international expert haematologists, including new co-editor Mark H. Yazer MD. A succinct and user-friendly re...

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Bibliographic Details
Other Authors: Murphy, Michael F. (Michael Furber) (Editor), Roberts, David J. (David John) (Consultant hematologist) (Editor), Yazer, Mark H. (Editor)
Format: eBook
Language:English
Published: Oxford ; Hoboken, NJ : John Wiley & Sons Inc., 2017.
Edition:Fifth edition.
Subjects:
Blood > Transfusion.
Blood > Collection and preservation.
MEDICAL > Pharmacology.
Blood > Collection and preservation
Blood > Transfusion
Online Access:Click for online access
Table of Contents:
  • Title Page; Table of Contents; List of Contributors; Preface; 1 Introduction; Blood Donation Worldwide; Changing Landscape of Transfusion Risks; Immunohaematology; Clinical Use of Blood Components: Evolution Based on Evidence; Urgent Transfusion; Patients Requiring Chronic Transfusion Support; Obstetric, Neonatal and Paediatric Transfusion Medicine; Haemostasis and Transfusion; Cellular Therapies, Transplantation, Apheresis; The Future; Conclusion; References; Part I: Basic Principles of Immunohaematology; 2 Essential Immunology for Transfusion Medicine; Cellular Basis of the Immune Response.
  • B-Cell Activation and T-Cell-Dependent Antibody FormationHumoral Immune Response; Antibody Effector Functions; Red Blood Cell Antibodies Illustrating the Above Principles; Antibody and Complement-Mediated Blood Cell Destruction; Clinical Aspects Related to Alloimmunisation Against Blood Cell Antigens; References; Further Reading; 3 Human Blood Group Systems; Introduction; The ABO System; The Rh System; Other Blood Group Systems; Biological Significance of Blood Group Antigens; References; Further Reading; 4 Human Leucocyte Antigens; Introduction; HLA Class I Genes; HLA Class II Genes.
  • Genetic Organisation and Expression of HLA Class II GenesExpression of HLA Molecules; Genetics; Function of HLA Molecules; Identification of HLA Gene Polymorphism; Formation of HLA Antibodies; Detection of HLA Antibodies; Clinical Relevance of HLA Antigens and Antibodies; HLA and Disease; References; Further Reading; 5 Platelet and Neutrophil Antigens; Antigens on Platelets and Granulocytes; Human Platelet Antigens; Human Neutrophil Antigens; References; Further Reading; 6 Pretransfusion Testing and the Selection of Red Cell Products for Transfusion; Introduction.
  • Determining the Recipient's ABO Group and Screening for Unexpected AntibodiesCrossmatching Techniques; Selection of Red Cells for Transfusion; Selection of Platelets and Plasma Components; References; Further Reading; Part II: Complications of Transfusions; 7 Investigation of Acute Transfusion Reactions; Introduction; Understanding the Clinical Presentation and Differential Diagnosis; General Approach for Investigation and Treatment of Acute Transfusion Reactions; Algorithm; References; Further Reading; 8 Haemolytic Transfusion Reactions; Definition of a Haemolytic Transfusion Reaction.
  • Pathophysiology of HTRsAcute HTRs; Delayed HTRs; Acute Haemolysis from ABO-Incompatible Platelet Transfusions; References; Further Reading; 9 Febrile and Allergic Transfusion Reactions; Introduction; Febrile Non-haemolytic Transfusion Reactions; Allergic Transfusion Reactions; References; 10 Lung Injury and Pulmonary Oedema After Transfusion; Definition; Incidence, Outcomes and Recipient Risk Factors; Clinical Manifestations; Differential Diagnosis; Pathogenesis; Lung Histology; Types of Blood Components That Can Cause TRALI; Mitigation Strategies; Patient Management; References.

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