Molecular Pathology : the Molecular Basis of Human Disease.

Saved in:
Bibliographic Details
Main Author: Coleman, William B.
Other Authors: Tsongalis, Gregory J.
Format: eBook
Language:English
Published: Saint Louis : Elsevier Science, 2017.
Edition:2nd ed.
Subjects:
Online Access:Click for online access

MARC

LEADER 00000cam a2200000Mi 4500
001 on1006403786
003 OCoLC
005 20240623213015.0
006 m o d
007 cr |n|---|||||
008 171014s2017 mou o 000 0 eng d
040 |a EBLCP  |b eng  |e pn  |c EBLCP  |d OCLCQ  |d LOA  |d OCLCO  |d OCLCF  |d OCLCO  |d K6U  |d OCLCQ  |d OCLCO  |d OCLCL  |d SXB 
020 |a 9780128027875 
020 |a 0128027878 
035 |a (OCoLC)1006403786 
050 4 |a RB113  |b .M654 2018 
049 |a HCDD 
100 1 |a Coleman, William B. 
245 1 0 |a Molecular Pathology :  |b the Molecular Basis of Human Disease. 
250 |a 2nd ed. 
260 |a Saint Louis :  |b Elsevier Science,  |c 2017. 
300 |a 1 online resource (805 pages) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
588 0 |a Print version record. 
505 0 |a Front Cover -- MOLECULAR PATHOLOGY -- MOLECULAR PATHOLOGY: THE MOLECULAR BASIS OF HUMAN DISEASE -- Dedication -- List of Contributors -- Preface -- 1 -- Molecular Mechanisms of Cell Death -- INTRODUCTION -- MODES OF CELL DEATH -- STRUCTURAL FEATURES OF NECROSIS AND APOPTOSIS -- Oncotic Necrosis -- Apoptosis -- CELLULAR AND MOLECULAR MECHANISMS UNDERLYING NECROTIC CELL DEATH -- Metastable State Preceding Necrotic Cell Death -- Mitochondrial Dysfunction and ATP Depletion -- Mitochondrial Uncoupling in Necrotic Cell Killing 
505 8 |a Mitochondrial Permeability TransitionInner Membrane Permeability -- Mitochondrial Permeability Transition Pore -- pH-dependent Ischemia/Reperfusion Injury -- Role of the Mitochondrial Permeability Transition in pH-Dependent Reperfusion Injury -- Oxidative Stress -- Protein Kinase Signaling and the MPT -- Other Stress Mechanisms Inducing Necrotic Cell Death -- Poly (ADP-Ribose) Polymerase -- Plasma Membrane Injury -- PATHWAYS TO APOPTOSIS -- Roles of Apoptosis in Biology -- Plasma Membrane -- MITOCHONDRIA -- Cytochrome c Release 
505 8 |a Regulation of the Mitochondrial Pathway to ApoptosisAntiapoptotic Survival Pathways -- NUCLEUS -- ENDOPLASMIC RETICULUM -- LYSOSOMES -- SHARED PATHWAYS TO NECROSIS AND APOPTOSIS -- PROGRAMMED NECROSIS -- Ferroptosis -- Pyroptosis -- Necroptosis -- CONCLUDING REMARK -- Acknowledgments -- References -- 2 -- Acute and Chronic Inflammation Induces Disease Pathogenesis -- INTRODUCTION -- LEUKOCYTE ADHESION, MIGRATION, AND ACTIVATION -- Endothelial Cell Expression of Adhesion Molecules -- Chemoattractants -- ACUTE INFLAMMATION AND DISEASE PATHOGENESIS 
505 8 |a PATTERN RECOGNITION RECEPTORS AND INFLAMMATORY RESPONSESToll-Like Receptors -- Cytoplasmic Sensors of Pathogens -- Pattern Recognition and Pathologic Consequences -- Innate Lymphoid Cells -- Regulation of Acute Inflammatory Responses -- CHRONIC INFLAMMATION AND ACQUIRED IMMUNE RESPONSES -- T-Lymphocyte Regulation of Chronic Inflammation -- B-Lymphocyte and Antibody Responses -- Exacerbation of Chronic Diseases -- TISSUE REMODELING DURING ACUTE AND CHRONIC INFLAMMATORY DISEASE -- Profibrogenic Cytokines and Growth Factors Involved in Fibrotic Tissue Remodeling 
505 8 |a TGFβTNFα -- References -- 3 -- Infection and Host Response -- INTRODUCTION -- MICROBES AND HOSTSâ#x80;#x94;BALANCE OF POWER? [1] -- THE STRUCTURE OF THE IMMUNE RESPONSE [2â#x80;#x93;4] -- REGULATION OF IMMUNITY [4] -- PATHOGEN STRATEGIES -- STAPHYLOCOCCUS AUREUS: THE EXTRACELLULARâ#x80;B̄ATTLEGROUND -- The Innate Immune System: Recognition of Pathogens -- Inhibition of Inflammatory Cell Recruitment and Phagocytosis [7â#x80;#x93;9] -- Inhibition of Complement Activation: You Canâ#x80;#x99;t Tag Me! [10] -- Inactivation of Antimicrobial Mechanisms [9,11] 
500 |a ""Staphylococcal Toxins and Superantigens: Turning the Inflammatory Response on the Host [12]"" 
650 0 |a Pathology, Molecular. 
650 0 |a Molecular biology. 
650 7 |a molecular biology.  |2 aat 
650 7 |a Molecular biology  |2 fast 
650 7 |a Pathology, Molecular  |2 fast 
700 1 |a Tsongalis, Gregory J. 
758 |i has work:  |a Molecular pathology (Text)  |1 https://id.oclc.org/worldcat/entity/E39PCGg8HVx6BBXDHPYDRQ8xKq  |4 https://id.oclc.org/worldcat/ontology/hasWork 
776 0 8 |i Print version:  |a Coleman, William B.  |t Molecular Pathology : The Molecular Basis of Human Disease.  |d Saint Louis : Elsevier Science, ©2017  |z 9780128027615 
856 4 0 |u https://ebookcentral.proquest.com/lib/holycrosscollege-ebooks/detail.action?docID=5090267  |y Click for online access 
903 |a EBC-AC 
994 |a 92  |b HCD