Regulating with RNA in Bacteria and Archaea

Regulating with RNA in Bacteria and Archaea

Revealing the many roles of RNA in regulating gene expressionFor decades after the discoveries of messenger RNA, transfer RNA, and ribosomal RNA, it was largely assumed that the role of RNA in the cell was limited to shuttling the genomic message, chaperoning amino acids, and toiling in the ribosome...

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Bibliographic Details
Main Author: Storz, Gisela
Other Authors: Papenfort, Kai
Format: eBook
Language:English
Published: Washington, DC : ASM Press, 2018.
Subjects:
Archaebacteria.
Bacteria.
Bacterial genetics.
Molecular microbiology.
RNA.
Archaebacteria
Bacteria
Bacterial genetics
Molecular microbiology
RNA
Online Access:Click for online access
Table of Contents:
  • Cover; Half Title; Title Page; Copyright Page; Contents; Contributors; Foreword; Preface; Acknowledgments; About the Editors; SECTION I: RNases and Helicases; Chapter 1: RNase E and the High-Fidelity Orchestration of RNA Metabolism; INTRODUCTION; A BRIEF EVOLUTIONARY HISTORY OF RNASE E; DOMAINS, MICRODOMAINS, AND PSEUDODOMAINS OF RNASE E; THE INTERACTION PARTNERS OF RNASE E; INTERACTION OF RNASE E WITH REGULATORY RNAs AND CHAPERONES; SUBSTRATE PREFERENCES OF RNASE E; ENCOUNTERING AND ACTING UPON SUBSTRATES; CELLULAR LOCALIZATION OF RNASE E AND THE DEGRADOSOME; SUMMARY AND PERSPECTIVES
  • SECTION II: Cis-Acting RNAsChapter 4: RNA Thermometers in Bacterial Pathogens; INTRODUCTION; CONTROL OF MASTER REGULATORS OF VIRULENCE; CONTROL OF IMMUNE EVASION AND EXTRACELLULAR FACTORS; QUORUM SENSING AND IRON ACQUISITION; OTHER VIRULENCE-RELATED FUNCTIONS; MUCH MORE TO COME?; References; Chapter 5: Small-Molecule-Binding Riboswitches; INTRODUCTION; RIBOSWITCHES-LOCATION, MECHANISM, AND DISTRIBUTION; THE TPP RIBOSWITCH-AN EXAMPLE ACROSS ALL DOMAINS OF LIFE; VERSATILITY OF RIBOSWITCHES; HOW TO FIND NEW RIBOSWITCHES; GETTING A GLIMPSE OF RIBOSWITCH STRUCTURE
  • SYNTHETIC RIBOSWITCHES-NOVEL MEANS FOR THE CONDITIONAL CONTROL OF GENE EXPRESSIONCONCLUDING REMARKS; References; Chapter 6: The T-Box Riboswitch: tRNA as an Effector to Modulate Gene Regulation; INTRODUCTION; DISCOVERY AND MECHANISM; CONSERVED ELEMENTS AND STRUCTURAL ORGANIZATION; PHYLOGENETIC DISTRIBUTION; T-BOX LEADER RNA-tRNA INTERACTIONS; STRUCTURAL ANALYSES OF T-BOX LEADER RNAs; THE T-BOX REGULATORY SYSTEM AS AN ANTIBIOTIC TARGET; CONCLUSIONS; References; Chapter 7: rRNA Mimicry in RNA Regulation of Gene Expression; THE rRNA AS A SOURCE OF RNA STRUCTURAL MOTIFS
  • R-PROTEINS AS AUTOGENOUS REGULATORSBEYOND AUTOGENOUS REGULATION: L7Ae; ENGINEERED r-PROTEIN-RESPONSIVE REGULATORY RNA SYSTEMS; CONCLUDING REMARKS; References; Chapter 8: Processive Antitermination; INTRODUCTION; PROCESSIVE ANTITERMINATION; SPECIALIZED NusG PARALOGS; OUTLOOK; References; Chapter 9: Genes within Genes in Bacterial Genomes; INTRODUCTION; INITIATION OF TRANSLATION IN BACTERIA; INTERNAL INITIATION FROM IN-FRAME START CODONS; INTERNAL INITIATION OF TRANSLATION THAT DIRECTS SYNTHESIS OF A PROTEIN FROM AN ALTERNATIVE READING FRAME

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