Interaction of nanomaterials with the immune system

Interaction of nanomaterials with the immune system / James C. Bonner, Jared M. Brown, editors.

This book covers the latest information related to understanding immune responses to engineered nanomaterials (ENMs). Many ENMs used in both the consumer and biomedical fields have been reported to elicit adverse immune responses ranging from innate immune responses such as complement activation to...

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Bibliographic Details
Other Authors: Bonner, James C., Brown, Jared M.
Format: eBook
Language:English
Published: Cham : Springer, 2020.
Series:Molecular and integrative toxicology.
Subjects:
Nanostructured materials > Physiological effect.
Nanostructured materials
Online Access:Click for online access
Table of Contents:
  • Overview of immune response to nanomaterials caused by either inhalation, oral, or dermal exposure
  • Engineered nanomaterials: synthesis, characterization, uses and exposure
  • Impact of nanomaterials on barrier function
  • Complement activation and inflammation
  • Macrophage function and phagocytosis
  • Mast cells
  • Impact on dendritic cell
  • lymphocyte function
  • Impact on host pathogen response and microbiome
  • Allergy/autoimmunity
  • Pre-existing allergic or bacterial-induced lung disease
  • Nanomaterial effects on viral infection
  • Immunotoxicity and carcinogenesis
  • In vivo animal models (nude mice, transgenic models)
  • In vitro cell culture models
  • In silico computational modeling
  • Summary of mechanisms of immune modulation.

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