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|a com.springer.onix.9789811516955
|b Springer Nature
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|a Model organisms for microbial pathogenesis, biofilm formation and antimicrobial drug discovery /
|c Busi Siddhardha, Madhu Dyavaiah, Asad Syed, editors.
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| 264 |
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1 |
|a Singapore :
|b Springer,
|c [2020]
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| 300 |
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|a 1 online resource :
|b illustrations
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| 336 |
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|a text
|b txt
|2 rdacontent
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|a Online resource; title from PDF title page (EBSCO, viewed April 10, 2020).
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|a Includes bibliographical references.
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|a "This book provides essential insights into microbial pathogenesis, host-pathogen interactions, and the anti-microbial drug resistance of various human pathogens on the basis of various model organisms. The initial sections of the book introduce readers to the mechanisms of microbial pathogenesis, host-pathogen interactions, anti-microbial drug resistance, and the dynamics of biofilm formation. Due to the emergence of various microbial resistant strains, it is especially important to understand the prognosis for microbial infections, disease progression profiles, and mechanisms of resistance to antibiotic therapy in order to develop novel therapeutic strategies. In turn, the second part of the book presents a comparative analysis of various animal models to help readers understand microbial pathogenesis, host-pathogen interactions, anti-microbial drug discovery, anti-biofilm therapeutics, and treatment regimes. Given its scope, the book represents a valuable asset for microbiologists, biotechnologists, medical professionals, drug development researchers, and pharmacologists alike."--
|c Provided by publisher
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|a Intro -- Preface -- Contents -- Editors and Contributors -- About the Editors -- Contributors -- 1: Microbial Infections and Virulence Factors -- 1.1 Introduction -- 1.1.1 Colonization of Host Surfaces by Pathogenic Microorganisms -- 1.1.2 Initiation and Maintenance of Pathogens in Intracellular Lifestyle -- 1.1.3 Crossing of Host Barriers by Pathogens -- 1.2 Microbial Infections -- 1.2.1 Bacterial Infections -- 1.2.2 Fungal Infections -- 1.2.3 Viral Infections -- 1.3 Virulence Factors Associated with Microbial Infections -- 1.3.1 Extracellular Virulence Factors
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| 505 |
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|a 1.3.2 Cell Associated Virulence Factors -- 1.4 Conclusion -- References -- 2: Microbial Pathogenesis: Virus Pathogen-Host Interactions -- 2.1 Introduction -- 2.2 Historical Views of Host-Microbe Interactions -- 2.2.1 Fundamental Properties of Viruses -- 2.2.1.1 Principal Rules of Virus-Host Interactions -- 2.2.2 Host Defense Mechanisms -- 2.2.2.1 Defensive Host and Unwearied Pathogens -- 2.2.3 Different Types of Virus-Host Interactions -- 2.2.3.1 Transient Infections -- 2.2.3.2 Acute Infections -- 2.2.3.3 Latent Infections -- 2.2.3.4 Persistent Infections
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|a 2.2.4 Virus-Host Interactions -- 2.2.4.1 Virus-Host Interactions: Attachment and Entry -- 2.2.4.2 Virus-Host Interactions: Reprogramming the Metabolism -- 2.2.4.2.1 General Trends of Metabolic Changes -- 2.2.5 Virus-Host Interactions: Reprogramming the Changes in Structure and Function of Cell Organelles -- 2.2.6 Future Directions of Virus-Host-Pathogen Interactions -- 2.3 Conclusion -- References -- 3: A Physical Insight of Biofilms -- 3.1 Introduction -- 3.2 Single Particle Tracking Method -- 3.3 Relevance of Physical Properties in Biofilms Formation -- 3.4 Branching Patterns
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| 505 |
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|a 3.5 Recent Observations on Biofilms -- References -- 4: A Review on Microbial Pathogenesis and Host Response -- 4.1 Introduction -- 4.1.1 Host-Microbe Relationship -- 4.1.1.1 Mutualism -- 4.1.1.2 Commensalism -- 4.1.1.3 Parasitism -- 4.2 Routes of Infection and Progression -- 4.2.1 Adhesion -- 4.2.2 Internalization -- 4.2.3 Colonization -- 4.2.4 Microbial Secretion System -- 4.3 Microbial Pathogenesis and Host Immune Response -- 4.3.1 Innate Immune Response -- 4.3.2 Adaptive or Specific Immune Responses -- 4.4 Conclusion -- References
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| 505 |
8 |
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|a 5: Role of Quorum Sensing in Microbial Infections and Biofilm Formation -- 5.1 Introduction -- 5.2 The Bacterial Chatter's -- 5.3 Quorum Sensing: The Bacterial Language -- 5.4 Biofilm Formation and Bacterial Infections Control by Quorum Sensing -- 5.5 Applications of Quorum Sensing in Biotechnology -- 5.6 Biofilm Matrix Composition and Architecture -- 5.6.1 Biofilm Matrix Composition -- 5.6.2 Biofilm Architecture -- 5.6.3 Biofilm Role in Human Infections -- 5.7 Applications of Biofilm in Biotechnology -- 5.8 Conclusion -- References
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|a 6: Microbial Pathogenesis and Antimicrobial Drug Resistance
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| 650 |
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|a Pathogenic microorganisms.
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| 650 |
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|a Host-parasite relationships.
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| 650 |
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|a Drug resistance in microorganisms.
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| 650 |
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|a Communicable diseases
|x Pathogenesis.
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| 650 |
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|a Biofilms.
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| 650 |
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|a Anti-infective agents.
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| 650 |
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7 |
|a Anti-infective agents
|2 fast
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| 650 |
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|a Biofilms
|2 fast
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| 650 |
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|a Communicable diseases
|x Pathogenesis
|2 fast
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| 650 |
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|a Drug resistance in microorganisms
|2 fast
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| 650 |
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|a Host-parasite relationships
|2 fast
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| 650 |
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|a Pathogenic microorganisms
|2 fast
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| 655 |
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|a Electronic books.
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| 700 |
1 |
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|a Siddhardha, Busi,
|e editor.
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| 700 |
1 |
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|a Dyavaiah, Madhu,
|e editor.
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| 700 |
1 |
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|a Syed, Asad,
|e editor.
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| 758 |
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|i has work:
|a Model Organisms for Microbial Pathogenesis, Biofilm Formation and Antimicrobial Drug Discovery (Text)
|1 https://id.oclc.org/worldcat/entity/E39PCYBDt4ddMQqr66RPyW6DfV
|4 https://id.oclc.org/worldcat/ontology/hasWork
|
| 776 |
0 |
8 |
|i Print version:
|a Siddhardha, Busi.
|t Model Organisms for Microbial Pathogenesis, Biofilm Formation and Antimicrobial Drug Discovery.
|d Singapore : Springer Singapore Pte. Limited, ©2020
|z 9789811516948
|
| 856 |
4 |
0 |
|u https://holycross.idm.oclc.org/login?auth=cas&url=https://link.springer.com/10.1007/978-981-15-1695-5
|y Click for online access
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| 903 |
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|a SPRING-BIOMED2020
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| 994 |
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|a 92
|b HCD
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