Bioactive natural products in drug discovery / Joginder Singh, Vineet Meshram, Mahiti Gupta, editors.

This book highlights different natural products that are derived from the plants and microbes that have shown potential as the lead compounds against infectious diseases and cancer. Natural products represent an untapped source of strikingly diverse chemotypes with novel mechanisms of action and the...

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Bibliographic Details
Other Authors: Singh, Joginder, Meshram, Vineet, Gupta, Mahiti
Format: eBook
Language:English
Published: Singapore : Springer, 2020.
Subjects:
Online Access:Click for online access

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245 0 0 |a Bioactive natural products in drug discovery /  |c Joginder Singh, Vineet Meshram, Mahiti Gupta, editors. 
260 |a Singapore :  |b Springer,  |c 2020. 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file 
347 |b PDF 
505 0 |a Intro -- Preface -- Contents -- About the Editors -- Part I: Plants Natural Products: Fountainheads for Drug Discovery and Development -- 1: The Artemisia Genus: Panacea to Several Maladies -- 1.1 Introduction -- 1.2 Phytochemistry -- 1.3 Conservation of Artemisia Species -- 1.4 Conclusions -- References -- 2: Bacopa monnieri: The Neuroprotective Elixir from the East-Phytochemistry, Pharmacology, and Biotechnological Improvement -- 2.1 Introduction -- 2.2 Methodology -- 2.3 Bioactivity Study -- 2.3.1 Biological Activities of Plant Extract(s) -- 2.3.1.1 Pro-cognitive Activity 
505 8 |a 2.3.1.2 Anti-neurodegenerative Activity -- 2.3.1.3 Antidepressant and Anti-stress Activity -- 2.3.1.4 Neuroprotective Activity -- 2.3.1.5 Cardioprotection -- 2.3.1.6 Gastrointestinal and Hepatoprotective Activity -- 2.3.1.7 Antiemetic Activity -- 2.3.1.8 Anti-epileptic Activity -- 2.3.1.9 Antioxidant Activity -- 2.3.1.10 Miscellaneous Activity -- 2.3.2 Pharmacological Activity of the Active Compounds -- 2.3.2.1 Bacoside A -- Anti-Alzheimerś Activity -- Anti-apoptotic Activity -- Anti-epileptic Activity -- Antidepressant Activity -- Anti-dopaminergic Activity -- Anti-inflammatory Activity 
505 8 |a Antioxidant Activity -- Hepatoprotection -- Neuroprotection -- Protease Inhibition Activity -- Renoprotective Activity -- Wound-Healing Activity -- 2.3.2.2 Bacopaside I -- 2.3.2.3 Betulinic Acid -- 2.3.3 Pharmacological Activity of the Polyherbal Formulation(S) -- 2.3.3.1 Cognition -- 2.3.3.2 Hepatic Encephalopathy -- 2.4 Biotechnological Advancement -- 2.5 Toxicity Study -- 2.6 Drug Designing -- 2.7 Structure-Activity Relationship -- 2.8 Summary -- 2.9 Conclusion -- References 
505 8 |a 3: Current Knowledge of Cinnamomum Species: A Review on the Bioactive Components, Pharmacological Properties, Analytical and B ... -- 3.1 Introduction -- 3.2 Botanical Description -- 3.3 Distribution -- 3.4 Traditional Use and Polyherbal Formulation of Cinnamon -- 3.5 Pharmacological Property of Cinnamomum Species -- 3.5.1 Anti-inflammatory Activity -- 3.5.2 Antibacterial Activity -- 3.5.3 Antifungal Activity -- 3.5.4 Antiviral Activity -- 3.5.5 Antioxidant Activity -- 3.5.6 Anticancer Activity -- 3.5.7 Gastroprotective Activity -- 3.5.8 Hypoglycemic/Anti-lipidemic Activity 
505 8 |a 3.5.9 Immunomodulatory Properties -- 3.5.10 Neuroprotective Activity -- 3.5.11 Cardioprotective Activity -- 3.6 Phytochemistry of Cinnamon -- 3.7 Clinical Study Based on Cinnamon -- 3.8 Extraction and Isolation of Bioactive Phytochemicals -- 3.9 Biotechnological Techniques for Large-Scale Multiplication of Cinnamomum Species -- 3.10 Molecular Markers for Genetic Diversity Assessment of Cinnamomum Species -- 3.11 Discussion and Conclusion -- References -- 4: Swertia spp.: A Potential Source of High-Value Bioactive Components, Pharmacology, and Analytical Techniques -- 4.1 Introduction 
500 |a Includes index. 
520 |a This book highlights different natural products that are derived from the plants and microbes that have shown potential as the lead compounds against infectious diseases and cancer. Natural products represent an untapped source of strikingly diverse chemotypes with novel mechanisms of action and the potential to serve as anticancer and anti-infective agents. The book discusses a range of biotechnologically valuable bioactive compounds and secondary metabolites that have been derived from plant and microorganisms from various ecological niches. It also reviews the latest developments in the field of genomics, bioinformatics and industrial fermentation for harnessing the microbial products for commercial applications. In turn, the books closing section reviews important biotechnological applications of various natural products. Combining the expertise of specialists in this field, the books goal is to promote the further investigation of natural sources for the development of standardized, safe and effective therapies. 
650 0 |a Drug development. 
650 0 |a Natural products. 
650 0 |a Pharmaceutical chemistry. 
650 0 |a Pharmacognosy. 
650 0 |a Materia medica, Vegetable. 
650 0 |a Medicine, Botanic. 
650 7 |a Pharmacognosy  |2 fast 
650 7 |a Medicine, Botanic  |2 fast 
650 7 |a Materia medica, Vegetable  |2 fast 
650 7 |a Drug development  |2 fast 
650 7 |a Natural products  |2 fast 
650 7 |a Pharmaceutical chemistry  |2 fast 
650 7 |a Botànica mèdica.  |2 thub 
650 7 |a Genètica vegetal.  |2 thub 
650 7 |a Farmacologia.  |2 thub 
655 7 |a e-books.  |2 aat 
655 7 |a Livres numériques.  |2 rvmgf 
655 7 |a Llibres electrònics.  |2 thub 
700 1 |a Singh, Joginder. 
700 1 |a Meshram, Vineet. 
700 1 |a Gupta, Mahiti. 
776 0 8 |i Print version:  |z 9811513937  |z 9789811513930  |w (OCoLC)1122463986 
856 4 0 |u https://holycross.idm.oclc.org/login?auth=cas&url=https://link.springer.com/10.1007/978-981-15-1394-7  |y Click for online access 
903 |a SPRING-BIOMED2020 
994 |a 92  |b HCD