Nanostructures for antimicrobial and antibiofilm applications

Nanostructures for antimicrobial and antibiofilm applications / Ram Prasad, Busi Siddhardha, Madhu Dyavaiah, editors.

In the pursuit of technological advancement in the field of biotechnology and pharmaceutical industries to counteract health issues, bacterial infections remain a major cause of morbidity and mortality. The ability of bacterial pathogens to form biofilms further agglomerates the situation by showing...

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Bibliographic Details
Other Authors: Prasad, Ram, Siddhardha, Busi, Dyavaiah, Madhu
Format: eBook
Language:English
Published: Cham : Springer, 2020.
Series:Nanotechnology in the life sciences.
Subjects:
Nanostructured materials.
Nanotechnology.
Plant reproduction & propagation.
Botany & plant sciences.
Microbiology (non-medical)
Technology & Engineering > Nanotechnology & MEMS.
Science > Life Sciences > Botany.
Science > Life Sciences > Biology > Microbiology.
Nanostructured materials
Electronic books.
Online Access:Click for online access
Table of Contents:
  • Intro
  • Preface
  • Contents
  • Contributors
  • About the Editors
  • Chapter 1: Nanomaterials: Therapeutic Agent for Antimicrobial Therapy
  • 1.1 Introduction
  • 1.1.1 Basic Discussion About Bacterial Cells
  • 1.1.2 How Nanomaterials or Antibacterial Agent Interact with Bacteria: Probable Mechanism
  • 1.1.2.1 Interaction of Nanomaterials with Bacterial Cell Membrane
  • 1.1.2.2 Release of Compounds/Metal Toxic to the Bacterial Cell
  • 1.1.2.3 Role of Reactive Oxygen Species (ROS) in Cell Damage
  • 1.1.2.4 Obstacle in Electron Transport and Protein Oxidation
  • 1.2 Essay for Measuring the Antimicrobial Activity of Nanomaterials
  • 1.2.1 Susceptibility of Nanomaterials Toward Microorganisms
  • 1.2.1.1 Dilution Method
  • 1.2.1.2 Disc-Diffusion Method
  • 1.2.2 Methods for Quantification of Antibacterial Activity
  • 1.2.2.1 Optical Density (OD) Measurement
  • 1.2.2.2 Cell Counting Method
  • 1.2.2.3 Spread-Plate Colony Counts
  • 1.2.2.4 Crystal Violet Staining
  • 1.2.2.5 Live/Dead Cell Staining and Imaging
  • 1.2.2.6 Tetrazolium Salt Reduction
  • 1.3 Role of Nanomaterials as Antimicrobial Agent
  • 1.3.1 The Ancient Era
  • 1.3.2 Why Nanomaterials Have Replaced the Ancient Antimicrobial Agents?
  • 1.4 Different Class of Nanomaterials Used as an Antimicrobial Agent
  • 1.4.1 Antimicrobial Properties of Silver-Based Nanomaterials
  • 1.4.2 Antimicrobial Activity of Zinc Oxide Nanomaterials (ZnO)
  • 1.4.3 Antimicrobial Activity of Titanium Oxide (TiO2) Nanomaterials
  • 1.4.4 Copper Nanomaterials as an Antimicrobial Agent
  • 1.4.5 Carbon-Based Nanomaterials as an Antimicrobial Agent
  • 1.4.5.1 Fullerene
  • 1.4.5.2 Carbon Nanotubes (CNTs)
  • 1.4.5.3 Graphene Oxide (GO)
  • 1.4.5.4 Activated Carbon-Based Nanomaterials (ACNMs)
  • 1.5 Challenges of Nanomaterials in Antibacterial Treatments
  • References
  • Chapter 2: A Review on Next-Generation Nano-Antimicrobials in Orthopedics: Prospects and Concerns
  • 2.1 Introduction
  • 2.2 Orthopedic Implants and Infections
  • 2.2.1 Planktonic
  • 2.2.2 Biofilm
  • 2.2.3 Invasive and Intracellular
  • 2.3 Bacterial Growth and Related Clinical Complications
  • 2.3.1 Cell Adhesion
  • 2.3.2 Cellular Aggregation
  • 2.3.3 Biofilm Maturation
  • 2.3.4 Cellular Detachment
  • 2.4 Conventional Techniques for Treating Infections
  • 2.5 Nanomaterials in Eradicating Infections
  • 2.6 Mechanism of Action for Nanobiotics
  • 2.7 Future Perspectives and Concerns
  • References
  • Chapter 3: Antibacterial Activity by Functionalized Carbon Nanotubes
  • 3.1 Introduction
  • 3.2 Synthesis of Functionalized Carbon Nanotubes
  • 3.3 Characterization of Functionalized Carbon Nanotubes
  • 3.4 Antimicrobial Activity of Functionalized Carbon Nanotubes
  • 3.4.1 Single-Walled Carbon Nanotubes
  • 3.4.2 Multiwalled Carbon Nanotubes
  • 3.5 Mechanisms of Action by Functionalized Carbon Nanotubes
  • 3.6 Conclusion
  • References

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