|
|
|
|
| LEADER |
00000cam a2200000 i 4500 |
| 001 |
on1228845452 |
| 003 |
OCoLC |
| 005 |
20240504213016.0 |
| 006 |
m o d |
| 007 |
cr ||||||||||| |
| 008 |
201206s2020 si ob 000 0 eng d |
| 040 |
|
|
|a UPM
|b eng
|e pn
|c UPM
|d OCLCO
|d OCLCQ
|d OCLCF
|d GW5XE
|d OCLCO
|d EBLCP
|d YDX
|d UKAHL
|d OCL
|d OCLCQ
|d OCLCO
|d COM
|d OCLCQ
|d AUD
|d OCLCQ
|d OCLCO
|d OCLCQ
|
| 019 |
|
|
|a 1226099397
|a 1226592213
|a 1228648966
|a 1241727518
|a 1269112068
|a 1287283953
|a 1287873140
|
| 020 |
|
|
|a 9789811591440
|q (electronic book)
|
| 020 |
|
|
|a 981159144X
|q (electronic book)
|
| 020 |
|
|
|z 9811591431
|
| 020 |
|
|
|z 9789811591433
|
| 024 |
7 |
|
|a 10.1007/978-981-15-9144-0
|2 doi
|
| 035 |
|
|
|a (OCoLC)1228845452
|z (OCoLC)1226099397
|z (OCoLC)1226592213
|z (OCoLC)1228648966
|z (OCoLC)1241727518
|z (OCoLC)1269112068
|z (OCoLC)1287283953
|z (OCoLC)1287873140
|
| 050 |
|
4 |
|a QH506
|
| 072 |
|
7 |
|a PSD
|2 bicssc
|
| 072 |
|
7 |
|a SCI056000
|2 bisacsh
|
| 072 |
|
7 |
|a PSD
|2 thema
|
| 072 |
|
7 |
|a UB
|2 thema
|
| 049 |
|
|
|a HCDD
|
| 100 |
1 |
|
|a Lü, Jinhu,
|e author.
|
| 245 |
1 |
0 |
|a Modeling and analysis of bio-molecular networks /
|c Jinhu Lü, Pei Wang.
|
| 264 |
|
1 |
|a Singapore :
|b Springer,
|c [2020]
|
| 300 |
|
|
|a 1 online resource
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a computer
|b c
|2 rdamedia
|
| 338 |
|
|
|a online resource
|b cr
|2 rdacarrier
|
| 347 |
|
|
|a text file
|
| 347 |
|
|
|b PDF
|
| 520 |
|
|
|a This book addresses a number of questions from the perspective of complex systems: How can we quantitatively understand the life phenomena? How can we model life systems as complex bio-molecular networks? Are there any methods to clarify the relationships among the structures, dynamics and functions of bio-molecular networks? How can we statistically analyse large-scale bio-molecular networks? Focusing on the modeling and analysis of bio-molecular networks, the book presents various sophisticated mathematical and statistical approaches. The life system can be described using various levels of bio-molecular networks, including gene regulatory networks, and protein-protein interaction networks. It first provides an overview of approaches to reconstruct various bio-molecular networks, and then discusses the modeling and dynamical analysis of simple genetic circuits, coupled genetic circuits, middle-sized and large-scale biological networks, clarifying the relationships between the structures, dynamics and functions of the networks covered. In the context of large-scale bio-molecular networks, it introduces a number of statistical methods for exploring important bioinformatics applications, including the identification of significant bio-molecules for network medicine and genetic engineering. Lastly, the book describes various state-of-art statistical methods for analysing omics data generated by high-throughput sequencing. This book is a valuable resource for readers interested in applying systems biology, dynamical systems or complex networks to explore the truth of nature.
|
| 505 |
0 |
|
|a 1 Introduction and Preliminaries -- 2 Reconstruction of Bio-molecular Networks -- 3 Modeling and Analysis of Simple Genetic Circuits -- 4 Modeling and Analysis of Coupled Bio-molecular Circuits -- 5 Modeling and Analysis of Large-scale Networks -- 6 Evolutionary Mechanisms of Network Motifs in PPI Networks -- 7 Identifying Important Nodes in Bio-molecular Networks -- 8 Statistical Analysis of Functional Genes in Human PPI Networks -- 9 Data-driven Statistical Approaches for Omics Data Analysis.
|
| 504 |
|
|
|a Includes bibliographical references.
|
| 588 |
0 |
|
|a Online resource; title from PDF title page (SpringerLink, viewed February 11, 2021).
|
| 650 |
|
0 |
|a Molecular biology
|x Data processing.
|
| 650 |
|
0 |
|a Computational biology.
|
| 650 |
|
0 |
|a Bioinformatics.
|
| 650 |
|
0 |
|a Biological systems
|x Research
|x Data processing.
|
| 650 |
|
0 |
|a Application software.
|
| 650 |
|
7 |
|a Molecular biology
|x Data processing
|2 fast
|
| 650 |
|
7 |
|a Computational biology
|2 fast
|
| 650 |
|
7 |
|a Application software
|2 fast
|
| 650 |
|
7 |
|a Bioinformatics
|2 fast
|
| 700 |
1 |
|
|a Wang, Pei,
|e author.
|
| 776 |
0 |
8 |
|i Print version:
|z 9789811591433
|
| 856 |
4 |
0 |
|u https://holycross.idm.oclc.org/login?auth=cas&url=https://link.springer.com/10.1007/978-981-15-9144-0
|y Click for online access
|
| 903 |
|
|
|a SPRING-COMP2020
|
| 994 |
|
|
|a 92
|b HCD
|