Essentials of blood product management in anesthesia practice

Essentials of blood product management in anesthesia practice / Corey S. Scher, Alan David Kaye, Henry Liu, Seth Perelman, Sarah Leavitt, editors.

This comprehensive book is written to inform and improve outcomes of patients in need of blood management during surgical procedures. Information is presented in an accessible format, allowing for immediate use in clinical practice. Beginning with an overview of the history of blood transfusions, ea...

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Bibliographic Details
Other Authors: Scher, Corey S. (Editor), Kaye, Alan David (Editor), Liu, Henry (Editor), Perelman, Seth (Editor), Leavitt, Sarah (Editor)
Format: eBook
Language:English
Published: Cham : Springer, [2021]
Subjects:
Anesthesia.
Blood > Transfusion.
Blood > Transfusion > Complications.
Blood products.
Anesthesia
Blood products
Blood > Transfusion
Blood > Transfusion > Complications
Online Access:Click for online access
Table of Contents:
  • Intro
  • Foreword
  • Contents
  • Contributors
  • 1: The History of Blood Transfusion and Blood Management
  • Introduction
  • The Legacy of Hippocrates
  • Antiquity and the Concept of Transfusion
  • The Discovery of the Circulation
  • The Cellular Elements of Blood
  • The Royal Society Transfusion Experiments
  • James Blundell and Obstetricians Revive Transfusion Medicine
  • The Legacy of Karl Landsteiner
  • The Search for an Anticoagulant
  • Fractionated Blood Products
  • Blood Management in the Modern Era
  • The Future of Blood Management
  • References
  • 2: Modern Blood Banking
  • The ABO and Rh Blood System
  • Other Blood Antigen Systems
  • The Human Leukocyte Antigen System
  • Alloimmunization
  • Inventory Management
  • RBC Considerations
  • Platelet Considerations
  • Plasma Considerations
  • Ordering Practices
  • Serologic Versus Computer Crossmatch
  • Emerging Infections
  • Arboviruses
  • Babesia Species
  • Creutzfeldt-Jakob Disease (CJD)
  • Pathogen Reduction Technology (PRT)
  • Conclusion
  • References
  • 3: Blood Component Therapy
  • Introduction
  • PRBCs
  • Fresh Frozen Plasma
  • Platelets
  • Cryoprecipitate
  • References
  • 4: The Coagulation System and Blood Clot Stability
  • Introduction
  • Coagulation Factors and Their Functions
  • Normal Coagulation Cascade
  • Regulation of Coagulation
  • Mechanisms of Clot Stability and Fibrinolysis
  • Factors Affecting Clot Stability
  • Fibrinolysis: Regulation and Its Role in Disease Process
  • Summary
  • References
  • 5: Fibrinolysis, Antifibrinolytic Agents, and Perioperative Considerations
  • Introduction
  • Fibrinolysis and Molecular Regulation
  • Measuring Fibrinolysis
  • Antifibrinolytic Agents
  • Tranexamic Acid
  • Epsilon-Aminocaproic Acid
  • Aprotinin
  • Perioperative Considerations
  • Cardiac Surgery
  • Tranexamic Acid and the Risk of Seizures
  • Trauma, the Role of Fibrinolysis, and Traumatic Brain Injury
  • Orthopedics
  • Liver Surgery and Transplantation
  • Obstetrics
  • Subarachnoid Hemorrhage
  • Pediatrics
  • Topical Tranexamic Acid
  • Conclusions
  • References
  • 6: Hypercoagulation and Thrombotic Disorders
  • Introduction
  • Hypercoagulable States
  • Primary (Congenital) Hypercoagulable States
  • Antithrombin Deficiency
  • Protein C and S Deficiency
  • Factor V Leiden (Activated Protein C Resistance)
  • Hyperhomocysteinemia
  • Other Primary Hypercoagulable States
  • Secondary (Acquired) Hypercoagulable States
  • Pregnancy/Puerperium
  • Oral Contraceptives and Hormone Replacement Therapy
  • Antiphospholipid Syndrome
  • Other Secondary Hypercoagulable States
  • Summary
  • References
  • 7: Diseases or Conditions of Platelet Disorders
  • Introduction
  • Types of Disorders
  • Thrombocytopenia
  • Thrombocythemia and Thrombocytosis
  • Inherited Platelet Disorders
  • Diagnosis
  • Management
  • Desmopressin
  • Platelet Concentrates
  • Recombinant Activated Factor VII (rFVIIa)
  • Antifibrinolytics
  • Hormonal Therapy

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