Landau-Kleffner syndrome and central auditory disorders in children / Makiko Kaga, Kimitaka Kaga.

This book addresses current topics concerning Landau-Kleffner Syndrome (LKS) and related central auditory disorders from the perspectives of epidemiology, diagnosis, genetics and clinical treatment. LKS is a rare childhood neurological disorder and manifests auditory agnosia as the central auditory...

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Bibliographic Details
Main Author: Kaga, Makiko
Other Authors: Kaga, Kimitaka, 1944-
Format: eBook
Language:English
Published: Singapore : Springer, 2021.
Series:Modern otology and neurotology.
Subjects:
Online Access:Click for online access
Table of Contents:
  • Intro
  • Preface
  • Contents
  • Chapter 1: Introduction
  • References
  • Part I: Landau-Kleffner Syndrome (LKS)
  • Chapter 2: History of LKS and Its Epidemiology
  • 2.1 History of LKS
  • 2.2 Epidemiology
  • References
  • Chapter 3: Diagnostic Paradigms
  • 3.1 Clinical Symptoms
  • 3.1.1 Onset of the Disease
  • 3.1.1.1 Auditory Verbal and Language Symptoms
  • 3.1.1.2 Musical Abilities
  • 3.1.2 LKS Patients' Subjective Awareness of Their Own Disease
  • 3.1.3 Behavioral Dysfunctions
  • 3.1.4 Family History
  • 3.1.5 Physical and Neuropsychological Examinations
  • 3.1.6 Intellectual Ability or IQs (Intellectual Quotients) in LKS Patients
  • 3.1.7 Epileptic Seizures
  • 3.2 Electroencephalography (EEG)
  • 3.3 Audiometric Findings in LKS Patients
  • 3.4 Evoked Responses in LKS Patients
  • 3.4.1 Auditory Brainstem Responses (ABR)
  • 3.4.2 Slow Vertex Responses (SVR)
  • 3.4.3 Combined Evoked Potentials (EPs) and Event-Related Responses (ERPs) in LKS Patients
  • 3.5 Event-Related Potentials
  • 3.5.1 Mismatched Negativity (MMN)
  • 3.5.2 The P300 Evoked Potential
  • 3.6 Blood Exams, Urinalysis, and CSF Measures
  • 3.7 Neuroimaging Examinations
  • 3.7.1 SPECT and PET Scan
  • 3.8 Magnetoenechalography (MEG)
  • References
  • Chapter 4: Etiology and Genetics
  • 4.1 Morphological Approach
  • 4.1.1 Gross Anatomical Approach
  • 4.1.2 Microscopic Approach
  • 4.2 Present Status in Delineating the Etiology of LKS
  • 4.2.1 LKS and Autism Spectrum Disorder (ASD)
  • 4.2.1.1 Autistic Regression and Language Regression
  • 4.3 Current Genetic Research
  • References
  • Chapter 5: Treatment and Long-Term Prognosis
  • 5.1 Epilepsy
  • 5.2 Surgical Interventions in the Treatment of LKS
  • 5.3 Speech and Language Training
  • References
  • Chapter 6: Case Histories
  • 6.1 Patient A: 4 Years Old, Female
  • 6.2 Patient B: 4 Years Old, Female
  • 6.3 Patient C: 6 Years Old, Male
  • 6.4 Patient D: 5 Years Old, Female
  • 6.5 Patient E: 8 Years Old, Male
  • 6.6 Patient F: 14 Years Old, Male
  • 6.7 Patient G: 8 Years Old, Male
  • 6.8 Patient H: 8 Years Old, Male
  • 6.9 Patient I: 10 Years Old, Female
  • Chapter 7: Fifty Years in the History of Landau-Kleffner Syndrome (LKS)
  • Part II: Related Central Auditory Disorders
  • Chapter 8: Adrenoleukodystrophy (ALD)
  • 8.1 Etiology and Clinical Course of the Disease
  • 8.2 Clinical Types of ALD and Their Signs and Symptoms
  • 8.3 Diagnosis of ALD
  • 8.4 Hearing Impairment in ALD
  • 8.5 Evaluation of Hearing in ALD
  • 8.6 Case Reports of Japanese Patients with ALD and Auditory Agnosia (Furushima et al. 2015)
  • 8.6.1 Case Histories of Three Patients
  • 8.6.1.1 Patient 1
  • 8.6.1.2 Patient 2
  • 8.6.1.3 Patient 3
  • 8.6.2 MRIs of the Above Patients
  • 8.6.2.1 Patient 1 (Fig. 8.4a)
  • 8.6.2.2 Patient 2 (Fig. 8.4b)
  • 8.6.2.3 Patient 3 (Fig. 8.4c)
  • 8.6.3 Audiograms
  • 8.6.4 ABR Findings
  • 8.6.5 SVR and MMN
  • 8.7 Summary
  • 8.7.1 Hearing Impairment