Cell biology and translational medicine. Volume 13, Stem cells in development and disease / Kursad Turksen, editor.

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work...

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Bibliographic Details
Other Authors: Turksen, Kursad (Editor)
Format: eBook
Language:English
Published: Cham : Springer, 2021.
Series:Advances in experimental medicine and biology ; v. 1341.
Subjects:
Online Access:Click for online access
Table of Contents:
  • Intro
  • Preface
  • Contents
  • Conventional and Emerging Markers in Stem Cell Isolation and Characterization
  • 1 Introduction
  • 2 Conventional Markers
  • 2.1 Neural Stem Cell (NSC) Markers
  • 2.2 Epidermal Stem Cell Markers
  • 2.3 Mesenchymal Stem Cell (MSC) Markers
  • 3 Emerging Markers
  • 3.1 Neural Stem Cell (NSC) Markers
  • 3.2 Epidermal Markers
  • 3.3 Cardiac Stem Cell Markers
  • 3.4 Osteoprogenitor Markers
  • 3.5 Mesenchymal Stem Cell (MSC) Markers
  • 3.6 Intestinal Stem Cell Markers
  • 4 Conclusion
  • References
  • Therapeutic Potential of Adipose Stem Cells
  • 1 Introduction
  • 2 ASCs in Regenerative Medicine
  • 2.1 ASCs as Therapy for Cardiac Disease
  • 2.2 ASCs and Biomaterials
  • 2.2.1 ASC and Biomaterials for Angiogenesis
  • 3 ASCs as Immunomodulators
  • 3.1 ASCs as Therapy for Autoimmune Diseases
  • 3.1.1 Multiple Sclerosis
  • 3.1.2 Rheumatoid Arthritis
  • 3.1.3 Type 1 Diabetes Mellitus
  • 3.2 ASCs in Neurodegenerative Diseases
  • 3.2.1 Alzheimerś Disease
  • 3.2.2 Parkinsonś Disease
  • 3.2.3 Amyotrophic Lateral Sclerosis
  • 4 Clinical Applications of ASCs
  • 4.1 Clinical Trials
  • 5 Future Directions
  • References
  • Decellularized Extracellular Matrix as a Potent Natural Biomaterial for Regenerative Medicine
  • 1 Introduction
  • 2 Natural Extracellular Matrix (ECM), a Naïve Version of ECM Versus Decellularized ECM (dECM)
  • 3 Versatility of Decellularization Protocols
  • 3.1 The Efficiency of Physical Methods for Decellularization
  • 3.2 The Efficiency of Chemical Methods for Decellularization
  • 3.3 Combined Chemical and Physical Methods for Decellularization
  • 3.4 Combination of Chemical and Enzymatic Methods for Decellularization
  • 3.5 The Combination of Physical, Chemical, and Enzymatic Methods for Decellularization
  • 4 Challenges Faced by Emerging Decellularization Technique
  • 5 Potential Opportunities and Possibilities
  • 5.1 Extracellular Matrix (ECM)-Based Bioink
  • 5.2 Particulate Form of the Extracellular Matrix (ECM)
  • 5.3 Mimicking the Vascular System
  • 6 Conclusion and Outlooks
  • References
  • Stem Cell Based Exosomes: Are They Effective in Disease or Health?
  • 1 Introduction
  • 2 Gene Delivery Systems
  • 3 Stem Cells and Their Exosomes
  • 3.1 Exosomes or Stem Cells?
  • 4 Synthetic Exosome-Mimics
  • 5 Banking of Exosomes
  • 5.1 Exosome Isolation and Characterization Methods
  • 5.2 Exosomes Storage Conditions
  • 6 Manufacturing Exosomes
  • 7 Conclusion
  • References
  • Interests of Exosomes in Bone and Periodontal Regeneration: A Systematic Review
  • 1 Introduction
  • 2 Materials and Methods
  • 2.1 Focused Question
  • 2.2 Screening and Selection Criteria
  • 2.3 Eligibility Criteria
  • 2.4 Outcomes
  • 3 Results
  • 3.1 Study Selection
  • 3.2 Studies Characteristics
  • 3.3 Induction of the Periodontal or Bony Defect
  • 3.4 Exosomes Sources
  • 3.5 Mode of Exosomes Administration and Dose
  • 3.6 Timing and Administration of Exosomes.