High altitude sickness -- solutions from genomics, proteomics and antioxidant interventions

High altitude sickness -- solutions from genomics, proteomics and antioxidant interventions / Narendra Kumar Sharma, Aditya Arya, editors.

This book reviews the recent advances in the development of proteomics-based biomarkers for the non-invasive diagnosis of altitude sickness and explores the potential of antioxidant therapy for this sickness. The first chapters introduce the associated pathophysiology and provide mechanistic insight...

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Bibliographic Details
Other Authors: Sharma, Narendra Kumar, Arya, Aditya
Format: eBook
Language:English
Published: Singapore : Springer, 2022.
Subjects:
Mountain sickness.
Anoxemia.
Anoxemia
Mountain sickness
Anoxèmia.
Llibres electrònics.
Online Access:Click for online access
Description
Summary:This book reviews the recent advances in the development of proteomics-based biomarkers for the non-invasive diagnosis of altitude sickness and explores the potential of antioxidant therapy for this sickness. The first chapters introduce the associated pathophysiology and provide mechanistic insights into the enhanced generation of reactive oxygen and nitrogen species (RONS), which leads to an increase in oxidative damage to lipids, proteins, and DNA. The book then highlights the current problems relating to the diagnosis and treatment of altitude sickness and summarizes novel approaches for identifying potential biomarkers and therapeutics. Lastly, it explores the therapeutic efficacy of antioxidant agents.
Item Description:5.4 Organ-Level Oxidative Damage Manifested by Cellular ROS
Physical Description:1 online resource (222 pages)
ISBN:9789811910081
9811910081
Source of Description, Etc. Note:Online resource; title from PDF title page (SpringerLink, viewed July 11, 2022).

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