Vertebrate motoneurons

Vertebrate motoneurons / Michael J. O'Donovan, Mélanie Falgairolle, editors.

This book aims to provide a comprehensive and timely review of new findings in motoneuron research. Recent findings have revealed that motoneurons are more complex and have more extensive functions than previously imagined. Some of the molecular and genetic pathways that orchestrate the development...

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Bibliographic Details
Other Authors: O'Donovan, Michael J., Falgairolle, Mélanie
Format: eBook
Language:English
Published: Cham : Springer, 2022.
Series:Advances in neurobiology ; 28.
Subjects:
Motor neurons.
Motor neurons
Neurones motores.
Llibres electrònics.
Online Access:Click for online access
Table of Contents:
  • Intro
  • Preface
  • Contents
  • Part I: Motoneuron Development
  • Establishing the Molecular and Functional Diversity of Spinal Motoneurons
  • 1 Introduction
  • 2 Anatomical and Functional Diversity of Spinal Motoneurons
  • 3 Specification of Spinal Motoneuron Class Identity
  • 4 Early Patterning of Spinal Motoneurons Along the Rostrocaudal Axis
  • 5 Developmental Mechanisms of Motoneuron Diversification
  • Hox Genes and the Specification of LMC Neurons and Divisional Subtypes
  • Intrinsic Programs of Motoneuron Pool Specification
  • Target-Dependent Regulation of Motoneuron Pool Identities
  • Development of Phrenic Motor Column (PMC) Neurons
  • Development and Diversity of Preganglionic Column (PGC) Neurons
  • Specification Hypaxial (HMC) and Medial Motor Column (MMC) Neurons
  • Establishing Motoneuron Functional Subtype Diversity
  • 6 Evolution of Spinal Motoneuron Organization and Function
  • Origins of Tetrapod Limb Motoneurons
  • Hox Genes and the Evolution of Motoneuron Segmental Organization and Diversity
  • Divergence of Axial Motoneuron Specification Programs in Fish
  • 7 Assembly of Proprioceptive Sensory-Motor Circuits
  • Specification of Proprioceptor Sensory Neuron Class Identities
  • Target-Derived Signals Regulate pSN Subtype Identity and Connectivity with Motoneurons
  • Roles of Motoneuron Subtype Identity in Sensory-Motor Circuit Assembly
  • Evidence for Coordinate Regulation of pSN-Motoneuron Connectivity by Hox Genes
  • 8 Motoneurons as Regulators of Circuit Assembly and Function
  • 9 Conclusions
  • References
  • Chloride Homeostasis in Developing Motoneurons
  • 1 Introduction
  • 2 NKCC1 and KCC2 Molecular Properties
  • 3 Chloride Homeostasis in Developing Motoneurons
  • Anatomical Maturation of CCCs
  • Modulation of the Chloride Homeostasis in Developing Motoneurons
  • Functional Consequences
  • 4 Pathological Considerations
  • 5 Concluding Remarks
  • References
  • Normal Development and Pathology of Motoneurons: Anatomy, Electrophysiological Properties, Firing Patterns and Circuit Connectivity
  • 1 Introduction and Historical Retrospective
  • 2 Classification of Motoneurons
  • 3 The Development of the Electrophysiological Properties and Firing Patterns of Motoneurons
  • 4 Development of Motoneuron Spinal Cord Circuitry
  • 5 Motoneuron Function Is Altered in Disease States
  • References
  • Homeostatic Regulation of Motoneuron Properties in Development
  • 1 Introduction
  • 2 Chick Embryo Homeostatic Plasticity
  • Synaptic Scaling
  • Homeostatic Intrinsic Plasticity
  • 3 Translation of Findings in Chick Embryo to Other Systems
  • Nicotine Exposure to Developing Rat Hypoglossal Motoneurons
  • Scaling Induced in Zebrafish Motoneurons Did Not Alter Motor Activity
  • Altered Levels of Neurotransmission Can Trigger HIP in Fly Motoneurons
  • 4 Novel Homeostatic Principles in Motoneurons from Studies in the Developing Fly and Frog

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