Fluorescence molecular tomography : principles and applications / Huabei Jiang.

Fluorescence Molecular Tomography: Principles and Applications is the first book to cover the underlying principles and practical applications of fluorescence molecular tomography (FMT) in a systematic manner. Using a tutorial approach, the text begins with an overview of the fundamentals of FMT and...

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Bibliographic Details
Main Author: Jiang, Huabei
Format: eBook
Language:English
Published: Cham, Switzerland : Springer, [2023]
Subjects:
Online Access:Click for online access

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245 1 0 |a Fluorescence molecular tomography :  |b principles and applications /  |c Huabei Jiang. 
260 |a Cham, Switzerland :  |b Springer,  |c [2023] 
300 |a 1 online resource 
505 0 |a Intro -- Preface -- Contents -- Chapter 1: Introduction -- 1.1 Fluorescence Molecular Tomography -- 1.2 Mathematic Image Reconstruction -- 1.2.1 Forward Problem: Fluorescent Photon Diffusion/Transport Model -- 1.2.2 Inverse Problem -- 1.3 Fluorescent Probes -- Chapter 2: Reconstruction Algorithms -- 2.1 Linear Reconstruction Algorithm -- 2.2 Nonlinear Reconstruction Algorithm -- 2.2.1 Algorithm Implementation -- 2.2.2 Results -- 2.2.3 Discussion -- Chapter 3: Instrumentation -- 3.1 Time-Domain FMT System -- 3.2 Frequency-Domain FMT System -- 3.3 CW-Domain FMT System 
505 8 |a 3.4 Contact vs. Noncontact Light Detection Scheme -- Chapter 4: Image Enhancing Schemes -- 4.1 Dual Mesh Scheme -- 4.2 RTE-Based Fluorescence Molecular Tomography -- 4.3 The Third-Order Diffusion Equations-Based FMT -- 4.4 DOT-Guided FMT -- 4.4.1 Methods and Materials -- 4.4.2 Results and Discussion -- 4.5 Fluorophore Lifetime Imaging -- 4.5.1 Methods and Materials -- 4.5.2 Results and Discussion -- 4.6 Full Density FMT -- 4.6.1 Methods -- 4.6.2 Results and Discussion -- Chapter 5: Bioluminescence Tomography -- 5.1 BLT Reconstruction Algorithm -- 5.1.1 Simulations -- 5.1.2 Experiments 
505 8 |a 5.1.3 Results and Discussion -- 5.2 DOT-Guided Bioluminescence Tomography -- 5.2.1 Methods -- 5.2.2 Results and Discussion -- Chapter 6: Multimodal Approaches -- 6.1 FMT/PAT -- 6.1.1 Methods -- 6.1.2 Results and Discussion -- 6.1.2.1 Comparison of Image Pattern -- 6.1.2.2 Comparison of Spatial Resolution -- 6.1.2.3 Comparison of Sensitivity -- 6.2 FMT/CT -- 6.3 FMT/Phase-Contrast CT -- 6.4 FMT/MRI -- 6.5 FMT/CT/SPECT -- Chapter 7: Miniaturized Fluorescence Molecular Tomography -- 7.1 Handheld FMT -- 7.1.1 Methods -- 7.1.2 Results and Discussion -- 7.1.2.1 Simulations 
505 8 |a 7.1.2.2 Phantom Experiments -- 7.1.2.3 Mouse Experiments -- 7.2 FMT Pen -- 7.2.1 Methods -- 7.2.2 Results and Discussion -- 7.2.2.1 Phantom Experiments -- 7.2.2.2 Animal Experiments -- 7.3 Endoscopic FMT -- 7.3.1 Methods -- 7.3.2 Results and Discussion -- Chapter 8: Animal Studies and Clinical Applications -- 8.1 Fruit Flies -- 8.1.1 Pupa with Dye-Containing Microtube -- 8.1.2 In Vivo Pupa with DsRed Reporter -- 8.2 Tumor Imaging in Animals -- 8.2.1 Ovarian Tumor -- 8.2.1.1 Methods -- Cell Lines and HER-2/Neu-Specific Affibody Conjugation to Magnetic Iron Oxide Nanoparticles (IONPs) 
505 8 |a Orthotopic Human Ovarian Cancer Xenograft Model -- Fluorescence Molecular Tomography Imaging System -- Photoacoustic Tomography System -- In Vivo Imaging in Animal Tumor Models -- Histology Analysis -- 8.2.1.2 Results and Discussion -- 8.2.2 Lung Tumor -- 8.2.2.1 Methods -- 8.2.2.2 Results and Discussion -- 8.2.3 Brain Tumor -- 8.2.3.1 Methods -- 8.2.3.2 Results and Discussion -- 8.3 Breast Tumor Imaging in Humans -- 8.3.1 Methods -- 8.3.2 Results and Discussion -- 8.4 Tumor Response to Therapies -- 8.4.1 Methods -- 8.4.2 Results and Discussion -- 8.5 Quantification of Receptor Density 
520 |a Fluorescence Molecular Tomography: Principles and Applications is the first book to cover the underlying principles and practical applications of fluorescence molecular tomography (FMT) in a systematic manner. Using a tutorial approach, the text begins with an overview of the fundamentals of FMT and goes on to detail image reconstruction approaches (including linear and nonlinear reconstruction algorithms), FMT instrumentations (including time-domain, frequency-domain, and continuous-wave domain systems), and implementation of image-enhancing schemes (including both software and hardware approaches). Further chapters examine multimodal approaches combining photoacoustic tomography (PAT), computed tomography (CT), single-photon emission tomography (SPECT), and magnetic resonance imaging (MRI) and discuss bioluminescence tomography and miniaturized FMT from hand-held to endoscopic FMT. A final chapter looks at clinical applications and animal studies. This authoritative and practical guide will serve as a valuable reference for researchers, scientists, clinicians, and industry professionals. The first book dedicated to fluorescence molecular tomography (FMT); Covers underlying principles and practical applications; Written by a leading FMT research pioneer and expert. 
504 |a Includes bibliographical references and index. 
588 0 |a Online resource; title from PDF title page (SpringerLink, viewed September 28, 2022). 
650 0 |a Fluorescence microscopy. 
650 0 |a Tomography. 
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650 7 |a Fluorescence microscopy  |2 fast 
650 7 |a Tomography  |2 fast 
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