Colorectal liver metastasis / Jean-Nicholas Vauthey, Yoshikuni Kawaguchi, René Adam, editors.

This book provides a practically applicable guide to the management of liver metastases in cases of colorectal cancer. It features detailed reviews of the latest diagnostic and therapeutic options. Instruction on how to appropriately apply surgical techniques including two stage hepatectomy as well...

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Bibliographic Details
Other Authors: Vauthey, Jean-Nicolas (Editor), Kawaguchi, Yoshikuni (Editor), Adam, R. (René) (Editor)
Format: eBook
Language:English
Published: Cham : Springer, [2022]
Subjects:
Online Access:Click for online access
Table of Contents:
  • Intro
  • Foreword
  • Foreword
  • Foreword
  • Preface
  • Acknowledgments
  • Contents
  • Contributors
  • Part I: Introduction
  • 1: History of Treatment of Colorectal Liver Metastases
  • 1.1 Introduction
  • 1.2 Early Liver Surgery for Colorectal Liver Metastases
  • 1.2.1 Anatomy
  • 1.2.2 Intraoperative Hemorrhage Control
  • 1.2.3 Tumour Identification
  • 1.3 Surgical Outcomes
  • 1.4 Cytotoxic and Biologic Agents
  • 1.5 Improved Patient Selection Based on Tumour Biology
  • 1.6 Conclusion
  • References
  • Part II: Surgery
  • 2: Liver Anatomy
  • 2.1 Introduction
  • 2.2 Functional "Unit" of the Liver
  • 2.2.1 Liver Segment and Terminology
  • 2.2.2 Liver Segmentation and Portal Territory
  • 2.2.3 Intersegmental Plane
  • 2.3 Portal Vein and Hepatic Vein
  • 2.3.1 Symmetrical Configuration of Portal and Venous Ramification Patterns
  • 2.3.2 Variation of Portal Vein and Hepatic Vein
  • 2.3.3 Venous Drainage Map
  • 2.4 Biliary Tract, Hepatic Artery, and Glissonian Pedicle
  • 2.4.1 Biliary Tract
  • 2.4.2 Hepatic Artery
  • 2.4.3 Glissonian Pedicle, Plate Systems, and Laennec's Capsule
  • 2.5 Caudate Lobe (Segment 1)
  • 2.6 Conclusion
  • References
  • 3: Exposure for Hepatectomy
  • 3.1 Introduction
  • 3.2 Incisions
  • 3.2.1 Midline Laparotomy
  • 3.2.2 J Incision (Makuuchi Incision)
  • 3.3 "Inverted-L" or Modified Makuuchi Incision
  • 3.4 Other Incisions
  • 3.5 Conclusion
  • References
  • 4: Parenchymal Preservation in the Operative Management of Colorectal Liver Metastases
  • 4.1 Introduction
  • 4.2 Perioperative Outcomes
  • 4.2.1 Perioperative Morbidity
  • 4.2.2 Perioperative Mortality
  • 4.3 Oncologic Outcomes
  • 4.3.1 Margins
  • 4.3.2 Recurrence and Survival
  • 4.3.3 Salvageability
  • 4.4 Special Considerations
  • 4.4.1 Genomic Profiling
  • 4.4.2 Minimally Invasive Surgery
  • 4.5 Conclusion
  • References.
  • 5: Simulation and Navigation
  • 5.1 Introduction
  • 5.2 Simulation
  • 5.2.1 Three-Dimensional Simulation Software and Virtual Hepatectomy
  • 5.3 Navigation
  • 5.3.1 Intraoperative Ultrasound
  • 5.3.2 Indocyanine Green Fluorescent Imaging
  • 5.3.3 Real-Time Virtual Sonography
  • 5.3.4 Navigation Software and Augmented Reality
  • 5.4 Conclusion
  • References
  • 6: Advanced Techniques in Multiple Metastases: Fiduciary Markers and Completion Ablation
  • 6.1 Introduction
  • 6.2 Fiducial Marker Placement
  • 6.2.1 Indication
  • 6.2.2 Procedure
  • 6.2.3 Results
  • 6.3 Completion Ablation (Planned Incomplete Resection and Postoperative Completion Ablation)
  • 6.3.1 Definition of Completion Ablation
  • 6.3.2 Indication
  • 6.3.3 Procedure
  • 6.3.4 Results
  • 6.4 Conclusions
  • References
  • 7: Two-Stage Hepatectomy for Bilateral Colorectal Liver Metastases: Experience of MD Anderson Cancer Center
  • 7.1 Introduction
  • 7.2 The MD Anderson Cancer Center Approach
  • 7.3 The MD Anderson Cancer Center "Fast-Track" Approach
  • 7.4 Outcomes After Two-Stage Hepatectomy
  • 7.5 Conclusion and Future Aims
  • References
  • 8: Two-Stage Hepatectomy for Bilobar Colorectal Liver Metastases: Experience of Hôpital Paul-Brousse
  • 8.1 Introduction
  • 8.2 Two-Stage Hepatectomy
  • 8.2.1 Indication
  • 8.2.2 Surgical Procedures of TSH
  • 8.2.3 Chemotherapy
  • 8.2.4 Dropout from the TSH Strategy
  • 8.2.5 Short-Term Outcome
  • 8.2.6 Long-Term Outcome
  • 8.2.7 Surgery for Recurrence
  • 8.2.8 Case Presentation
  • 8.3 Conclusion
  • References
  • 9: One-Stage Hepatectomy for Bilateral Colorectal Liver Metastases: Experience of the University of Tokyo
  • 9.1 Introduction
  • 9.2 Preoperative Evaluation
  • 9.2.1 Diagnostic Approach
  • 9.2.2 Evaluation of Liver Function and Future Liver Remnant Volume
  • 9.3 Intraoperative Inspection of CLMs.
  • 9.4 Outcomes after One-Stage Hepatectomy
  • 9.5 Future Perspective of One-Stage Hepatectomy
  • 9.6 Conclusion
  • References
  • 10: Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) for Colorectal Liver Metastasis
  • 10.1 Introduction
  • 10.2 Evolution of ALPSS as a New Surgical Strategy
  • 10.3 ALPPS for Colorectal Liver Metastases
  • 10.4 When Is ALPPS for CLM Functionally Indicated?
  • 10.4.1 Where Do We Come From? Functional Resectability in the Pre-ALPPS Era
  • 10.4.2 Functional Resectability With ALPPS
  • 10.5 ALPPS for CLM in a Curative Intention
  • 10.6 ALPPS in a Multimodal Treatment of CLM
  • 10.7 Conclusion
  • References
  • 11: Open Resection Technique
  • 11.1 Introduction
  • 11.2 Anaesthesia
  • 11.3 General Principles
  • 11.4 Access-Incision, Retraction, and Mobilization
  • 11.5 Intra-Operative Ultrasound
  • 11.6 Laparoscopy
  • 11.7 Pringle Manoeuvre
  • 11.8 Liver Dissection/Transection
  • 11.9 Inflow Control
  • 11.10 CUSA
  • 11.11 Intrahepatic Ligation
  • 11.12 Outflow Control
  • 11.13 Sealing the Parenchyma
  • 11.14 Wound Closure
  • 11.15 Special Situations
  • 11.16 Conclusion
  • References
  • 12: Laparoscopic Liver Resection Technique: The Norwegian Experience
  • 12.1 Introduction
  • 12.2 Laparoscopic Liver Resection for Colorectal Liver Metastases
  • 12.2.1 Selection and Limitations
  • 12.2.2 Surgical Techniques
  • 12.2.2.1 Laparoscopic Nonanatomic Resection (Cauliflower Technique)
  • 12.2.2.2 Left Lateral Sectionectomy
  • 12.2.2.3 Laparoscopic Left Hemihepatectomy
  • Liver Mobilization
  • Control of Vascular Inflow
  • Parenchymal Transection
  • Outflow Control
  • 12.2.2.4 Laparoscopic Right Hemihepatectomy
  • Liver Mobilization
  • Vascular Inflow Control
  • Parenchymal Transection
  • Hepatic Venous Outflow Control
  • 12.3 Conclusion/Personal Opinion
  • References.
  • 13: Laparoscopic Liver Resection Technique: French Experience
  • 13.1 Introduction
  • 13.2 Perioperative and Short-Term Outcomes
  • 13.3 Oncologic and Long-Term Outcomes
  • 13.4 Repeat Liver Resection
  • 13.5 Synchronous Resection of CLM
  • 13.6 Two-Stage Hepatectomy (TSH)
  • 13.7 Associating Liver Partition with Portal Vein Ligation (ALPPS)
  • 13.8 Technical Tips and Tricks
  • 13.8.1 Positioning
  • 13.8.2 Incisions, Exploration, and Exposure
  • 13.8.3 Transection Techniques
  • 13.8.4 Extraction, Drainage, and Closure
  • 13.9 Conclusions
  • References
  • 14: Laparoscopic Anatomical Liver Resection Technique: The Japanese Experience
  • 14.1 Introduction
  • 14.2 Techniques Based on the Anatomical Landmarks for LALR
  • 14.2.1 Glissonean Approach
  • 14.2.1.1 Anatomical Landmarks for Glissonean Approach
  • 14.2.1.2 Techniques of Glissonean Approach for LAR at Ageo Central General Hospital
  • Left Hepatectomy
  • Right Anterior Sectionectomy
  • Laparoscopic Parenchymal-Sparing Anatomical Liver Resection (Lap-PSAR)
  • 14.2.2 Parenchymal Transection on the Intersegmental Planes
  • 14.2.2.1 Anatomical Landmarks for the Hepatic Veins
  • Inferior Phrenic Vein (IPV)
  • Arantius Ligament
  • 14.2.2.2 Approaches for Exposing the HVs
  • 14.2.2.3 Parenchymal Transection under Indocyanine Green (ICG) Fluorescence Image Guidance at Ageo Central General Hospital
  • 14.3 Future Prospects (The Long-Term Advantages of LLR for CRLM)
  • 14.4 Conclusion
  • References
  • 15: Is There a Place for Robotic Resection?
  • 15.1 Introduction
  • 15.2 Rationale for Minimally Invasive Resection of Colorectal Liver Metastases
  • 15.2.1 Laparoscopic Hepatectomy
  • 15.2.2 Theoretical Advantages of a Robotic Approach
  • 15.3 Learning Curve
  • 15.4 Robotic Hepatectomy Outcomes
  • 15.4.1 Robotic Versus Open Perioperative Outcomes.
  • 15.4.2 Robotic Versus Laparoscopic Perioperative Outcomes
  • 15.4.3 Oncologic Outcomes
  • 15.4.4 Cost
  • 15.5 Limitations of Robotic Hepatectomy
  • 15.6 Robotic Surgery in Practice: Our Approach
  • 15.6.1 Patient Selection for Robotic Hepatectomy
  • 15.6.2 Technical Aspects of Robotic Hepatectomy
  • 15.6.2.1 Positioning and Setup
  • 15.6.2.2 Intraoperative Ultrasound
  • 15.6.2.3 Instrumentation and General Principles
  • 15.6.2.4 Right Hepatectomy
  • 15.6.2.5 Left Hepatectomy
  • 15.6.2.6 Partial Hepatectomy
  • 15.6.2.7 Perioperative Management for Robotic Hepatectomy
  • 15.7 Future Directions
  • 15.8 Conclusion
  • References
  • 16: Advanced Resection Technique with Vascular Reconstruction
  • 16.1 Introduction
  • 16.2 Rational for Resection and Reconstruction
  • 16.3 Advanced Technique for Resection of CLM
  • 16.3.1 Tumours Located in the Posterosuperior Segments
  • 16.3.2 Resection of Tumours Located at Central Upper Segments with Reconstruction of Hepatic Veins Confluence
  • 16.3.3 Central Lower Tumours with Portal and Biliary Reconstruction
  • 16.4 R1 Resection by Necessity Versus Complex Resection with Vascular Reconstruction
  • 16.5 Oncological Results of Complex Resection with Vascular Reconstruction in CLM
  • 16.6 Conclusion
  • References
  • 17: Resection Margins
  • 17.1 Introduction
  • 17.2 Resection Margins in Colorectal Liver Metastases
  • 17.2.1 Resection Margins Status as a Predictor of Tumour Recurrence and Overall Survival
  • 17.2.2 Resection Margins and Perioperative Chemotherapy
  • 17.2.3 Resection Margins and Parenchymal-Sparing Hepatectomy
  • 17.2.4 Resection Margins and Minimally Invasive Hepatectomy
  • 17.2.5 Resection Margins and Somatic Gene Mutations
  • 17.2.6 R1 Resection as a Predictor of Recurrence at the Hepatic Resection Margin
  • 17.3 Conclusion
  • References
  • 18: R1 Vascular Surgery.