Integrins in health and disease : key effectors of cell-matrix and cell-cell interactions / Donald Gullberg, Johannes A. Eble, editors.

Integrins are heterodimeric cell surface receptors which anchor cells to different extracellular matrix proteins or act as cell-cell receptors. They play pivotal roles not only across a wide range of physiological processes including tissue morphogenesis, wound healing, and regulation of cell growth...

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Bibliographic Details
Other Authors: Gullberg, Donald E. (Editor), Eble, Johannes A., 1964- (Editor)
Format: eBook
Language:English
Published: Cham : Springer, [2023]
Series:Biology of extracellular matrix ; v. 13.
Subjects:
Online Access:Click for online access
Table of Contents:
  • Part 1: Knockouts and animal models
  • Integrins 11 and 21 The generalist collagen receptors
  • Roles for Integrin 31 in Development and Disease
  • Part 2: Fibrosis& Cancer
  • Integrins: Key targets in tissue fibrosis and tumor stroma
  • Integrins in Cardiac Form, Function and Disease
  • Integrin 8 and its ligand nephronectin in health and disease
  • v integrin-dependent TGF activation in cancer: a brief update
  • Part 3: Human disease
  • a11b1, a mesenchymal collagen-binding integrin with a central role in tissue- and tumor fibrosis
  • Integrins in pathological tissue remodelling of joints
  • 4 integrins in immune homeostasis and disease
  • 2-integrins in immunity: new roles for old players
  • Structure and function of the leukocyte integrin M2
  • Part 4: Integrins in hemostasis, and immune control
  • Platelet integrins: Critical mediators of haemostasis and pathological thrombus formation
  • Integrins as receptors for bacterial and viral pathogens.