Endolysosomal voltage-dependent cation channels

Endolysosomal voltage-dependent cation channels / Christian Wahl-Schott, Martin Biel, editors.

This book covers the molecular structures and the cellular and in vivo function of endosomes and lysosomes, i.e. intracellular vesicles which are involved in many cellular processes such as endocytosis, intracellular trafficking, degradation of material from inside (e.g. autophagy) and outside the c...

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Bibliographic Details
Other Authors: Wahl-Schott, Christian (Editor), Biel, Martin (Editor)
Format: eBook
Language:English
Published: Cham : Springer, [2023]
Series:Handbook of experimental pharmacology ; v. 278.
Subjects:
Ion channels.
Endosomes.
Lysosomes.
Endosomes
Ion channels
Lysosomes
Online Access:Click for online access
Table of Contents:
  • Part I: Physiological Functions of Endo-lysosomal Cation Channels
  • NAADP-Mediated Ca2+ Signalling
  • NAADP-Dependent TPC Current
  • NAADP-Evoked Ca2+ Signaling: The DUOX2-HN1L/JPT2-Ryanodine Receptor 1 Axis
  • TPC Functions in the Immune System
  • Lysosomal Ion Channels and Lysosome- 1 Organelle Interactions
  • TRPML1 and TFEB, an Intimate Affair
  • Lysosomal Potassium Channels
  • Part II Structure and Composition of TPC and TRPML Channels
  • Structure and Function of Plant and Mammalian TPC Channels
  • A Structural Overview of TRPML1 and the TRPML Family
  • Endo-Lysosomal Two-Pore Channels and Their Protein Partners
  • Part III: Tools and Methods to Characterize Endolysosomal Cation Channels
  • Electrophysiological Techniques on the Study of Endolysosomal Ion Channels
  • The Plant Vacuole as Heterologous System to Characterize the Functional Properties of TPC Channels
  • Expanding the Toolbox: Novel Modulators of Endolysosomal Cation Channels
  • Characterization of Endo-Lysosomal Cation Channels Using Calcium Imaging.

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