Synopsis of pathophysiology in nuclear medicine / Abdelhamid H. Elgazzar.

This book, now in its second edition, will serve as a quick reference that will help the reader to understand different diagnostic scintigraphic patterns and to select appropriate treatment modalities based on functional imaging. The book concisely describes relevant anatomic and physiologic conside...

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Bibliographic Details
Main Author: Elgazzar, Abdelhamid H., 1949-
Format: eBook
Language:English
Published: Cham : Springer, 2023.
Edition:2nd ed.
Subjects:
Online Access:Click for online access
Table of Contents:
  • Intro
  • Preface to First Edition
  • Acknowledgment
  • Contents
  • 1: Pathophysiology: General Principles
  • 1.1 Introduction
  • 1.2 Pathology
  • 1.3 Definition of Disease
  • 1.3.1 Homeostasis
  • 1.3.2 The Genome
  • 1.4 Physiology
  • 1.5 Pathophysiology
  • 1.6 Basic Major Principles of Pathophysiology
  • 1.6.1 Cell Injury
  • 1.6.1.1 Biochemical Cell Injury Mechanisms
  • 1.6.1.2 Intracellular Accumulations
  • 1.6.2 Cell and Tissue Response to Injury
  • 1.6.2.1 Cell Adaptation
  • 1.6.2.1.1 Atrophy
  • 1.6.2.1.2 Hypertrophy
  • 1.6.2.1.3 Hyperplasia
  • 1.6.2.1.4 Metaplasia
  • 1.6.2.1.5 Dysplasia
  • 1.6.2.2 Cell Death
  • 1.6.2.2.1 Necrosis (Nonregulated, Inflammatory Accidental Cell Death)
  • 1.6.2.2.2 Apoptosis (Regulated, Noninflammatory Cell Death)
  • References
  • 2: Ionizing Radiation: Biologic Effects and Essential Cell and Tissue Biology
  • 2.1 Essential Cell and Tissue Biology
  • 2.1.1 Cell Structure and Function
  • 2.1.1.1 Plasma Membrane
  • 2.1.1.2 Cytoplasm and its Organelles
  • 2.1.1.2.1 The Endoplasmic Reticulum
  • 2.1.1.2.2 The Golgi Complex
  • 2.1.1.2.3 Lysosomes
  • 2.1.1.2.4 Peroxisomes
  • 2.1.1.3 Mitochondria
  • 2.1.1.4 Ribosomes
  • 2.1.1.5 Cytoskeleton
  • 2.1.1.6 Nucleus
  • 2.1.2 The Genetic Material and Gene Expression
  • 2.1.2.1 The Genetic Material: DNA
  • 2.1.2.1.1 DNA Structure
  • 2.1.2.1.2 DNA Replication
  • 2.1.2.1.3 DNA Mutation
  • 2.1.2.1.4 DNA Recombination
  • 2.1.2.2 Gene Expression and Protein Synthesis
  • 2.1.2.3 Genetic Code
  • 2.1.2.4 DNA Translation: Protein Synthesis
  • 2.1.3 Cell Reproduction
  • 2.1.3.1 The Cell Cycle
  • 2.1.3.2 Mitosis and Cytokinesis
  • 2.1.3.3 Rates of Cell Division
  • 2.1.3.4 Chromosomes and Diseases
  • 2.1.4 Cell Transformation and Differentiation
  • 2.1.5 Normal and Malignant Growth
  • 2.1.5.1 Normal Growth
  • 2.1.5.1.1 Types of Cells and Tissue
  • 2.1.5.1.2 MuscleTissue
  • Skeletal Muscle
  • Cardiac Muscle
  • Smooth Muscle
  • 2.1.5.1.3 Nerve Tissue
  • 2.1.5.1.4 Epithelial Tissue
  • 2.1.5.1.5 Matrix
  • 2.1.5.2 Indigenous Connective Tissue
  • 2.1.5.2.1 Fibroblasts
  • 2.1.5.2.2 Mast Cells
  • 2.1.5.2.3 Fat Cells
  • 2.1.5.2.4 Bone Cells
  • 2.1.5.2.5 Cartilage Cells
  • 2.1.5.2.6 Immigrant Cells
  • 2.1.5.3 Neoplastic Growth
  • 2.1.6 Cellular Metabolism
  • 2.1.6.1 Role of ATP
  • 2.1.6.2 Production of ATP
  • 2.1.6.2.1 Glycolysis
  • 2.1.6.2.2 Oxidative Phosphorylation
  • 2.1.7 Transport through the Cell Membrane
  • 2.1.7.1 Transport of Water and Solutes
  • 2.1.7.1.1 Diffusion
  • 2.1.7.1.2 Active-Mediated Transport
  • 2.1.7.1.3 Transport by Vesicle Formation
  • 2.1.7.1.4 Transport by Transmission of Electrical Impulses
  • 2.1.8 Cell Death (See also Chaps. 1 and 12)
  • 2.1.8.1 Imaging Cell Death
  • 2.2 Biologic Effects of Ionizing Radiation
  • 2.2.1 Ionizing Radiation
  • 2.2.2 Mechanisms of Radiation Effects
  • 2.2.2.1 Direct Effect
  • 2.2.2.2 Indirect Effect
  • 2.2.2.2.1 Bystander Effect