Smart nanomaterials targeting pathological hypoxia

Smart nanomaterials targeting pathological hypoxia / Sonam Chawla, Sachidanand Singh, Azamal Husen, editors.

The book showcases the newest research on smart nanoplatforms responding to hypoxia; an omnipresent pathological feature of many modern-day diseases and its potential applications. The book demonstrates the versatility of hypoxia targeted smart nanoplatforms in disease management in diverse patholog...

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Bibliographic Details
Other Authors: Chawla, Sonam, Singh, Sachidanand, Husen, Azamal
Format: eBook
Language:English
Published: Singapore : Springer, 2023.
Series:Smart nanomaterials technology.
Subjects:
Nanostructured materials.
Smart materials.
Nanostructured materials
Smart materials
Online Access:Click for online access
Table of Contents:
  • Intro
  • Preface
  • Contents
  • About the Editors
  • Smart Nanotechnology in Pathological Hypoxia: An Innovative Avenue for a Clinical Hurdle
  • 1 Introduction
  • 1.1 Molecular Responses to Hypoxia-Hypoxia-Inducible Factors and Allied Pathways
  • 2 Smart Nanomaterials
  • 2.1 Smart Nanomaterials Targeting Hypoxic Tissues
  • References
  • Bioinspired Nanosystems Interacting with the Host Environment: Smart Nanosystems
  • 1 Introduction
  • 2 Smart Nanosystems in Drug Delivery
  • 3 Targeted Drug Delivery Approaches
  • 4 Bioinspired Nanocarriers
  • 4.1 Lipid Nanostructures
  • 4.2 Lipid Nanoparticles (LNPs)
  • 4.3 Lipid Nanocapsules (LNCs)
  • 4.4 Lipid-Based Micelles
  • 4.5 Viral Vectors
  • 4.6 Liposome-Based Nanocarriers
  • 4.7 Polymeric Nanocarrier
  • 5 Nanorobotics
  • 5.1 Targeted Motion
  • 5.2 Drug Release Mechanism
  • 6 Potential and Limitations of Smart Nanosystem
  • 7 Conclusion
  • References
  • Nanotechnology-Based Approaches to Relieve Tumour Microenvironment Hypoxia via Enhanced Oxygen Delivery
  • 1 Introduction
  • 2 Nanotechnology-Based Approaches for O2 Delivery in Hypoxic Site
  • 2.1 Nanochemical Decomposition for O2 Release
  • 2.2 Breakdown of Catalase to Generate O2
  • 2.3 Water-Based Splitting to Produce O2
  • 3 Various Strategically Used Nanomaterials for TME Hypoxia
  • 3.1 PFC-Based Oxygen Carriers (PFOCs) and Fe2+ Porphyrin Systems
  • 3.2 Artificial Red Blood Cells Substitute (RBCSs)
  • 3.3 Metal-Organic Framework (MOFs)
  • 3.4 Oxygen Microcapsules
  • 4 Nanotechnology-Based Therapeutic Approaches for Hypoxia
  • 4.1 Nanoparticles Conquering Hypoxia-Inducing Factor
  • 4.2 Targeting Metastatic Hypoxic Condition by Nanodelivery Against Chemoresistance
  • 4.3 Nanoparticle Relieving: Lowering Hypoxic TME by Immunotherapy
  • 5 Conclusion
  • References
  • Recent Progress in Hypoxia-Targeting: Peptide-Based Nanomaterials
  • 1 Introduction
  • 2 Polypeptide-Based Nanoparticles
  • 3 Self-Assembled Peptide-Based Nanoparticles
  • 4 Peptide and Polymer Conjugate Nanoparticles
  • 5 Peptide-Functionalized Liposomes
  • 6 Polysaccharides Functionalization Study by Peptides
  • 7 Conclusion and Outlook for the Future
  • References
  • Recent Advancements in the Field of Stimuli-Responsive Polymeric Nanomaterials for Cancer Treatment
  • 1 Introduction
  • 2 Smart Polymeric Nanobiomaterials
  • 2.1 The Preparation Process of Stimuli-Responsive Polymers
  • 3 Physicochemical Characterization
  • 3.1 Single Stimuli-Responsive Smart Materials
  • 3.2 Dual Stimuli-Responsive Smart Materials
  • 3.3 Multi-stimuli-Responsive Smart Materials
  • 4 Anti-tumor Efficiency of Stimuli-Responsive Nanopolymers
  • 4.1 Single Stimuli-Responsive Smart Materials
  • 4.2 Dual Stimuli-Responsive Smart Materials
  • 4.3 Multi-stimuli-Responsive Smart Materials
  • 5 Conclusion
  • References

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