Bioinformatics and Biomedical Engineering : Part I / 10th International Work-Conference, IWBBIO 2023, Meloneras, Gran Canaria, Spain, July 12-14, 2023, Proceedings. Ignacio Rojas, Olga Valenzuela, Fernando Rojas Ruiz, Luis Javier Herrera, Francisco Ortuño, editors.

This volume constitutes the proceedings of the 10th International Work-Conference on IWBBIO 2023, held in Meloneras, Gran Canaria, Spain, during July 12-14, 2022. The total of 79 papers presented in the proceedings, was carefully reviewed and selected from 209 submissions. The papers cove the latest...

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Bibliographic Details
Corporate Author: IWBBIO (Conference) Gran Canaria, Canary Islands)
Other Authors: Rojas, Ignacio (Editor), Valenzuela, Olga (Editor), Rojas Ruiz, Fernando (Editor), Herrera, Luis Javier (Editor), Ortuño, Francisco (Francisco Manuel) (Editor)
Format: eBook
Language:English
Published: Cham : Springer, 2023.
Series:Lecture notes in computer science. Lecture notes in bioinformatics.
Lecture notes in computer science ; 13919.
LNCS sublibrary. Bioinformatics.
Subjects:
Online Access:Click for online access
Table of Contents:
  • Intro
  • Preface
  • Organization
  • Contents - Part I
  • Contents - Part II
  • Analysis of Molecular Dynamics Data in Proteomics
  • Recognition of Conformational States of a G Protein-Coupled Receptor from Molecular Dynamic Simulations Using Sampling Techniques
  • 1 Introduction
  • 2 Materials and Methods
  • 2.1 Class Imbalance Correction Methods
  • 2.2 Experimental Setup
  • 2.3 Evaluation Metrics for Imbalanced Data Problems
  • 3 Results and Discussion
  • 3.1 Interpretation Results
  • 4 Conclusions
  • References
  • Identification of InhA-Inhibitors Interaction Fingerprints that Affect Residence Time
  • 1 Introduction
  • 1.1 Ligand-Receptor Binding Kinetics
  • 1.2 Computer Methods to Determine Binding Kinetic Parameters
  • 1.3 Research Objective
  • 2 Mycobacterium Enoyl Acyl Carrier Protein Reductase (InhA)
  • 3 Methods
  • 4 Results
  • 4.1 Ligand Similarity
  • 4.2 Drug-Like Ligand Properties that Affect Residence Time
  • 5 Discussion and Conclusions
  • References
  • Bioinformatics
  • Validation of Height-for-Age and BMI-for-Age Z-scores Assessment Using Android-Based Mobile Apps
  • 1 Introduction
  • 2 Methods
  • 2.1 Subjects
  • 2.2 Anthropometric Measurements
  • 2.3 Z-score Calculation
  • 2.4 Statistical Analysis
  • 3 Outcomes
  • 4 Discussion
  • 5 Conclusion
  • 6 Limitations
  • References
  • An Algorithm for Pairwise DNA Sequences Alignment
  • 1 Introduction
  • 2 Related Work
  • 3 An Algorithm for Pairwise DNA Sequences Alignment Based on the Proposed CAT Method
  • 4 Experimental Results and Analysis
  • 4.1 Implementation of the Proposed Method CAT for Sequences Alignment
  • 4.2 Collision Analysis
  • 4.3 Performance Analysis
  • 5 Conclusion
  • References
  • Multiallelic Maximal Perfect Haplotype Blocks with Wildcards via PBWT
  • 1 Introduction
  • 2 Finding Maximal Blocks with Wildcards
  • 3 The Algorithm
  • 3.1 Positional BWT Extended to Wildcards
  • 3.2 Building the Extended PBWT
  • 3.3 Computing the Maximal Blocks
  • 4 Experimental Results
  • 5 Conclusions
  • References
  • GPU Cloud Architectures for Bioinformatic Applications
  • 1 Introduction
  • 2 GPU Usage in Bioinformatics
  • 3 Processing Outsourcing
  • 4 GPU Virtualisation in Cloud Architectures
  • 5 Architecture Characteristics
  • 6 Experiments
  • 7 Conclusions
  • References
  • Biomarker Identification
  • Novel Gene Signature for Bladder Cancer Stage Identification
  • 1 Introduction
  • 2 Data Description
  • 3 Metodology
  • 3.1 Differential Expressed Genes Extraction and Visualization
  • 3.2 Development of Classification Models
  • 4 Results and Discussion
  • 4.1 Gene Enrichment
  • 5 Conclusions
  • References
  • Predicting Cancer Stage from Circulating microRNA: A Comparative Analysis of Machine Learning Algorithms
  • 1 Introduction
  • 2 Materials and Methods
  • 2.1 Study Cohort
  • 2.2 Algorithms
  • 2.3 Evaluation Metrics
  • 2.4 Experimental Design