Advances in radiation oncology in lung cancer

Advances in radiation oncology in lung cancer / Branislav Jeremić, editor.

This is the third, completely updated edition of a comprehensive book in which many of the worlds leading lung cancer specialists discuss the recent advances in the radiation oncology of lung cancer and reflect on the latest research findings in lung cancer and other intrathoracic malignancies. Lung...

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Bibliographic Details
Other Authors: Jeremić, Branislav (Editor)
Format: eBook
Language:English
Published: Cham, Switzerland : Springer, 2023.
Edition:Third edition.
Series:Medical radiology (Series)
Subjects:
Lungs > Cancer > Radiotherapy.
Cancer > Radiotherapy.
Radiotherapy.
Diagnostic imaging.
Online Access:Click for online access
Table of Contents:
  • Intro
  • Preface
  • Contents
  • Part I: Basic Science of Lung Cancer
  • Genomic Alterations in Lung Cancer
  • 1 Introduction
  • 2 NSCLC
  • 3 EGFR
  • 4 ALK
  • 5 ROS1
  • 6 BRAF
  • 7 MET
  • 8 RET
  • 9 NTRK
  • 10 HER2
  • 11 KRAS
  • 12 FGFR
  • 13 Small Cell Lung Cancer
  • 14 Conclusion
  • References
  • Epigenetic Events in Lung Cancer
  • 1 Introduction
  • 2 Classification of the Epigenetic Modifications
  • 2.1 DNA Methylation
  • 2.2 Regulators of the Chromatin Structure: Histone Modifiers
  • 2.2.1 Histone Acetyltransferases
  • 2.2.2 Histone Deacetylases
  • 2.2.3 Histone Methyltransferases
  • 2.2.4 Histone Demethylases
  • 2.3 Regulators of the Chromatin Structure: Chromatin Remodeling Complexes
  • 3 Landscape of the Epigenetic Abnormalities in Lung Cancer
  • 3.1 Aberrant DNA Methylation
  • 3.2 Gene Abnormalities Affecting Chromatin Remodelers: The SWI/SNF Complex
  • 3.3 Abnormalities in Histone Modifiers
  • 4 Epigenetic-Based Therapeutic Strategies in Lung Cancer
  • 4.1 DNA Methyltransferase Inhibitors
  • 4.2 Histone Deacetylase Inhibitors
  • 4.3 Other Epigenetic Inhibitors
  • 5 Conclusions and Future Directions
  • References
  • Part II: Clinical Investigations
  • Interventional Pulmonology
  • 1 Introduction
  • 2 Diagnostic Techniques
  • 2.1 Autofluorescence Videobronchoscopy
  • 2.2 Narrow-Band Imaging
  • 2.3 Endobronchial Ultrasound
  • 2.4 Recent Diagnostic Techniques in Interventional Pulmonology
  • 3 Therapeutic Techniques
  • 3.1 Techniques with Immediate Effect
  • 3.1.1 Nd:YAG and Ho:YAG Laser Photoresection
  • 3.1.2 Electrocautery
  • 3.1.3 Argon Plasma Coagulation
  • 3.2 Techniques with Delayed Effect
  • References
  • Pathology of Lung Cancer
  • 1 Introduction
  • 2 Adenocarcinoma
  • 2.1 Background
  • 2.2 Major Adenocarcinoma Patterns
  • 2.3 Adenocarcinoma Variants
  • 2.4 Nonmucinous Adenocarcinoma Classification
  • 2.5 Grading of Lung Adenocarcinoma
  • 2.6 Staging Issues Associated with Adenocarcinoma
  • 3 Squamous Cell Carcinoma
  • 3.1 Background
  • 3.2 Histology of Squamous Cell Carcinoma
  • 3.3 Differentiation of Primary Squamous Cell Carcinoma of the Lung from Metastatic Squamous Cell Carcinoma
  • 4 Adenosquamous Carcinoma
  • 5 Pleomorphic Carcinoma
  • 6 Neuroendocrine Neoplasms of the Lung
  • 6.1 Background
  • 6.2 Histology of Neuroendocrine Neoplasms
  • 6.3 Immunohistochemistry for Neuroendocrine Neoplasms
  • 6.4 Ki-67 Proliferative Index for Pulmonary Neuroendocrine Neoplasms
  • 7 Molecular Diagnostics in NSCLC and Triage of Limited Tissue Samples for Comprehensive Diagnosis
  • 8 Pathology Assessment of Post-Neoadjuvant Resections for NSCLC
  • References
  • Role of Radiologic Imaging in Lung Cancer
  • 1 Introduction, Technical Advances
  • 2 Diagnosis of Lung Cancer/Solitary Pulmonary Nodule
  • 3 T Staging/NSCLC
  • 4 N Staging/NSCLC
  • 5 M Staging/NSCLC
  • 6 CT in Treatment Response Assessment and Follow-Up of NSCLC
  • References

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