Uncommon ulcers of the extremities / Ajay K. Khanna, Satyendra Kumar Tiwary, editors.

The book covers all uncommon ulcers of the extremities which remain a difficult diagnosis for clinicians most of the times. A variety of causes like metabolic, infective, rheumatoid, drug induced or inflammation may lead to ulcerations. Diagnosis of these ulceration is difficult as these diseases ar...

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Bibliographic Details
Format: eBook
Language:English
Published: Singapore : Springer, 2023.
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Online Access:Click for online access
Table of Contents:
  • Intro
  • Preface
  • Contents
  • Editors and Contributors
  • About the Editors
  • Contributors
  • 1: Approach to a Case of Ulcer of Extremity
  • 1.1 Prevalence
  • 1.2 Relevant Points of Interest
  • 1.3 Common Ulcerations Causes (Table 1.1)
  • 1.4 Step-Wise Approach
  • 1.5 Conclusion
  • References
  • 2: Hypertensive/Martorell Ulcer
  • 2.1 Introduction
  • 2.2 Pathogenesis
  • 2.3 Clinical Presentation
  • 2.4 Differential Diagnosis
  • 2.5 Diagnosis
  • 2.5.1 Diagnostic Criteria
  • 2.6 Histopathological Diagnosis
  • 2.7 Management
  • 2.8 Skin Grafting
  • 2.9 Pain Management
  • 2.10 General Measures
  • 2.11 Management of Residual Wounds
  • 2.12 Prognosis
  • 2.13 Clinical Pearls
  • 3: Rheumatoid Ulcers
  • 3.1 Introduction
  • 3.2 Epidemiology of Rheumatoid Limb Ulcers
  • 3.3 Pathogenesis
  • 3.3.1 Vasculitis and Inflammation
  • 3.3.2 Differential Load Distribution
  • 3.3.3 Associated Conditions
  • 3.3.4 Iatrogenic
  • 3.3.5 Impaired Healing
  • 3.4 Clinical Features
  • 3.4.1 Vasculitic Ulcers of the Extremities
  • 3.4.2 Pyoderma Gangrenosum
  • 3.5 Diagnosis
  • 3.6 Management
  • 3.6.1 Local Wound Care
  • 3.6.2 Coverage for Secondary Infections
  • 3.6.3 Systemic Immunosuppression
  • 3.6.4 Management of Pyoderma Gangrenosum
  • 3.7 Conclusion
  • References
  • 4: Ulcers in Systemic Sclerosis
  • 4.1 Introduction
  • 4.1.1 Systemic Sclerosis: Definition and Prevalence
  • 4.2 Diagnostic Criteria of Systemic Sclerosis
  • 4.2.1 Ulcers in Systemic Sclerosis
  • 4.3 Pathogenesis of Vascular Disease in Systemic Sclerosis
  • 4.3.1 Pathogenesis of Ulcers
  • 4.3.2 Ulcers over the Sites of Calcinosis
  • 4.4 Clinical Features
  • 4.5 Investigations
  • 4.6 Management
  • 4.6.1 Lifestyle Changes
  • 4.6.2 Drug Treatment
  • 4.6.3 Prostanoids (Level of Evidence: Meta-Analysis)
  • 4.6.4 Endothelin Receptor-1 Antagonists (Level of Evidence: Meta-Analysis)
  • 4.6.5 Phosphodiesterase Type-5 Inhibitors (Level of Evidence: Meta-Analysis)
  • 4.6.6 Calcium Channel Blockers (Level of Evidence: Randomized Controlled Trial)
  • 4.6.7 Combination Therapy (Level of Evidence: Case Report)
  • 4.6.8 Other Drug Therapies that Have Been Explored
  • 4.6.8.1 Statins (Level of Evidence: Randomized Controlled Trial)
  • 4.6.8.2 Anticoagulant and Antiplatelet Agents (Level of Evidence: Randomized Controlled Trial)
  • 4.6.9 Surgical Strategies
  • 4.6.9.1 General Approach
  • 4.6.9.2 Sympathectomy and Injection of Botulinum Toxin (Level of Evidence: Retrospective Case Series and Case Series)
  • 4.6.10 Prognosis
  • References
  • 5: Livedoid Vasculopathy: Clinical, Histopathological, and Therapy Evaluation
  • 5.1 Introduction
  • 5.2 Our Casuistic
  • 5.3 Methods
  • 5.4 Results
  • 5.5 Discussion
  • 5.6 Hallmarks of the Literature
  • 5.7 Conclusions
  • References
  • 6: Ulcers in Hypercoagulable States
  • 6.1 Introduction
  • 6.2 General Pathogenesis of Cutaneous Ulcers in Hypercoagulable States