Glycoscience: Chemistry and Chemical Biology I–III

Glycoscience: Chemistry and Chemical Biology I–III edited by Bertram O. Fraser-Reid, Kuniaki Tatsuta, Joachim Thiem.

Glycoscience has become a term covering all sorts of activities and applications within or at the edge of carbohydrate research. Glycostructures play a highly diverse and crucial role in a myriad of organisms and important systems in biology, physiology, medicine, bioengineering and technology. Only...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Fraser-Reid, Bertram O. (Editor), Tatsuta, Kuniaki (Editor), Thiem, Joachim (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2001.
Edition:1st ed. 2001.
Series:Springer eBook Collection.
Subjects:
Organic chemistry.
Biochemistry.
Molecular biology.
Biotechnology.
Pharmacology.
Food—Biotechnology.
Electronic resources (E-books)
Online Access:Click to view e-book
Holy Cross Note:Loaded electronically.
Electronic access restricted to members of the Holy Cross Community.
Table of Contents:
  • Volume I
  • 1 General Principles
  • 1.1 Structure and Conformation of Carbohydrates
  • 1.2 Properties of Carbohydrates
  • 1.3 Separation and Purification of Carbohydrates
  • 1.4 General Occurrence of Carbohydrates
  • 2 General Synthetic Methods: Reactions at Non Anomeric Positions
  • 2.1 Reactions at Oxygen Atoms
  • 2.2 Oxidation and Reduction
  • 2.3 Deoxygenation
  • 2.4 Heteroatom Exchange
  • 2.5 Anhydrosugars
  • 2.6 C-C Bond Formation
  • 2.7 C=C Bond Formation
  • 2.8 Degradation Reactions
  • 2.9 Rearrangement Reactions
  • 3 General Synthetic Methods: Reactions at the Anomeric Center
  • 3.1 Reactions at Oxygen Atoms
  • 3.2 Oxidation, Reduction and Deoxygenation
  • 3.3 Heteroatom Exchange: Glycosylation
  • 3.3.1 Mechanistic Aspects
  • 3.3.2 Glycosides as Donors
  • 3.3.3 Glycosyl Halides and Anomeric Esters as Donors
  • 3.4 Anomeric Anhydro Sugars
  • 3.5 S-Glycosylation
  • 3.6 N-Glycosylation
  • 3.7 C-Glycosylation
  • 3.8 Formation and Reactions of Glycal Derivatives
  • 3.9 Degradation and Rearrangement Reactions
  • Volume II
  • 4 Monosaccharides
  • 4.1 Occurrence and Significance
  • 4.2 Properties
  • 4.3 Synthesis of Biologically Relevant Monosaccharides
  • 4.4 De Novo Synthesis of Monosaccharides
  • 4.5 Formation of Complex Natural Compounds from Monosaccharides
  • 4.6 Biosynthesis and Degradation
  • 4.7 Chemical Biology and Biomedicine
  • 5 Oligosaccharides
  • 5.1 Occurrence and Significance
  • 5.2 Properties
  • 5.3 Synthesis
  • 5.3.1 Enzymatic Glycosylation
  • 5.3.2 Glycosyl Halides in Oligosaccharide Synthesis
  • 5.3.3 Regio-and Stereoselective Methods of Glycosylation
  • 5.3.4 Stereoselective Synthesis of ß-manno Glycosides
  • 5.3.5 Combinatorial and Solid Phase Methods in Oligosaccharide Synthesis
  • 5.4 Biosynthesis and Degradation of Galactosyloligosaccharides ....
  • 5.5 Chemical Biology and Biomedicine
  • 5.5.1 Glycosylphosphatidylinositols
  • 5.5.2 Mammalian Carbohydrate-Lectin Interactions
  • 5.5.3 Multivalency in Protein-Carbohydrate Recognition
  • Volume III
  • 6 Complex Polysaccharides
  • 6.1 Occurrence and Significance
  • 6.2 Properties
  • 6.3 Synthesis of Sulfated Glycosaminoglycans
  • 6.4 Biosynthesis and Degradation
  • 6.5 Chemical Biology and Biomedicine
  • 6.5.1 General Aspects
  • 6.5.2 Mycobacterial Cell Wall Components
  • 7 Glycolipids
  • 7.1 Occurrence and Significance
  • 7.2 Properties
  • 7.3 Synthesis
  • 7.4 Biosynthesis and Degradation
  • 7.5 Chemical Biology and Biomedicine: Glycolipids and Glycosphingolipids
  • 8 Glycoproteins
  • 8.1 Occurrence and Significance
  • 8.2 Properties
  • 8.3 Synthesis and Applications of Biologically Relevant Glycopeptides
  • 8.4 Chemical Biology and Biomedicine: Enkephalin-Derived Glycopeptide Analgesics
  • 9 Other Glycoconjugates
  • 9.1 Antitumor and Antimicrobial Glycoconjugates
  • 9.2 Synthesis of Enediyne Antibiotic Oligosaccharides
  • 9.3 Chemical Biology and Biomedicine of Glycosylated Natural Compounds
  • 10 Glycomimetics
  • 10.1 Introduction
  • 10.2 Azaglycomimetics: Synthesis and Chemical Biology
  • 10.3 Carbasugars: Synthesis and Functions
  • 10.4 Sulfur Containing Glycomimetics
  • 10.5 C-Glycosyl Analogs of Oligosaccharides and Glycosyl Amino Acids
  • 10.6 Non-Sugar Glycomimetics
  • IUPAC’s 1996 Recommendations on Nomenclature of Carbohydrates.

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