Identification of novel modulators towards high cell density and high-producing Chinese hamster ovary suspension cell cultures as well as their application in biopharmaceutical protein production / submitted by Beat Thalmann, Dipl. Chemist (FH), MSc Biotechnology (FH), from Berg am Irchel (ZH), Fischingen (TG) and Pfungen (ZH), Switzerland.
Long description: Amongst the mammalian producer cell lines, the Chinese hamster ovary (CHO) cell lines are of predominant importance in biopharmaceutical production. Thus, novel factors increasing overall productivity are sought and bear the potential to reduce the unit costs of a production proces...
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